HCSGD entry for BMP1
1. General information
| Official gene symbol | BMP1 |
|---|---|
| Entrez ID | 649 |
| Gene full name | bone morphogenetic protein 1 |
| Other gene symbols | OI13 PCOLC PCP PCP2 TLD |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001501 | Skeletal system development | NAS | biological_process |
| GO:0001502 | Cartilage condensation | TAS | biological_process |
| GO:0001503 | Ossification | IEA | biological_process |
| GO:0004222 | Metalloendopeptidase activity | IEA TAS | molecular_function |
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005578 | Proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0006508 | Proteolysis | IDA IEA | biological_process |
| GO:0007275 | Multicellular organismal development | TAS | biological_process |
| GO:0008083 | Growth factor activity | IEA | molecular_function |
| GO:0008233 | Peptidase activity | IDA | molecular_function |
| GO:0008237 | Metallopeptidase activity | NAS | molecular_function |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0030154 | Cell differentiation | IEA | biological_process |
| GO:0030198 | Extracellular matrix organization | TAS | biological_process |
| GO:0031988 | Membrane-bounded vesicle | IEA | cellular_component |
| GO:0042157 | Lipoprotein metabolic process | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
| GO:0061036 | Positive regulation of cartilage development | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5913284792 | 0.3081477641 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.1562573503 |
| GSE13712_SHEAR | Down | -0.2614118821 |
| GSE13712_STATIC | Down | -0.3322933472 |
| GSE19018 | Up | 0.0281370408 |
| GSE19899_A1 | Down | -0.0501247685 |
| GSE19899_A2 | Up | 0.0271427767 |
| PubMed_21979375_A1 | Up | 0.1385764840 |
| PubMed_21979375_A2 | Up | 0.3286699511 |
| GSE35957 | Down | -0.2770592794 |
| GSE36640 | Up | 0.0116775945 |
| GSE54402 | Down | -0.3955872753 |
| GSE9593 | Up | 0.1385740357 |
| GSE43922 | Up | 0.0299039155 |
| GSE24585 | Down | -0.1640474973 |
| GSE37065 | Down | -0.1859961334 |
| GSE28863_A1 | Up | 0.6710920890 |
| GSE28863_A2 | Up | 0.4010377843 |
| GSE28863_A3 | Down | -0.0424307491 |
| GSE28863_A4 | Down | -0.1849139602 |
| GSE48662 | Up | 0.4924185148 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-29b-3p | MIMAT0000100 | MIRT006060 | Luciferase reporter assay//Microarray//qRT-PCR | Functional MTI | 19956414 |
| hsa-miR-335-5p | MIMAT0000765 | MIRT018244 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-204-5p | MIMAT0000265 | NA | hsa-miR-204 | 20369013 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
