HCSGD entry for ST8SIA1

1. General information

Official gene symbolST8SIA1
Entrez ID6489
Gene full nameST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1
Other gene symbolsGD3S SIAT8 SIAT8-A SIAT8A ST8SiaI
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003828Alpha-N-acetylneuraminate alpha-2,8-sialyltransferase activityIEAmolecular_function
GO:0005794Golgi apparatusIEAcellular_component
GO:0005975Carbohydrate metabolic processTASbiological_process
GO:0006486Protein glycosylationIEAbiological_process
GO:0006688Glycosphingolipid biosynthetic processTASbiological_process
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0008373Sialyltransferase activityIEA TASmolecular_function
GO:0016021Integral component of membraneIEA TAScellular_component
GO:0030173Integral component of Golgi membraneIEAcellular_component
GO:0034605Cellular response to heatIEAbiological_process
GO:0097503SialylationTASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.15308668360.87969192280.77996389421.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0329163004
GSE13712_SHEARDown-0.0156403290
GSE13712_STATICDown-0.1496289153
GSE19018Up0.0816547426
GSE19899_A1Up0.1863618049
GSE19899_A2Down-0.1287769966
PubMed_21979375_A1Up0.0308592425
PubMed_21979375_A2Up0.0364809323
GSE35957Up0.1420756338
GSE36640Up0.1594704697
GSE54402Down-0.1205489084
GSE9593Up1.0405998554
GSE43922Down-0.0278321167
GSE24585Up0.0698378812
GSE37065Down-0.0362877229
GSE28863_A1Up0.3383906826
GSE28863_A2Up0.1198565132
GSE28863_A3Down-0.0748388454
GSE28863_A4Up0.0300673813
GSE48662Up0.6547559987

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.