HCSGD entry for USP46
1. General information
| Official gene symbol | USP46 |
|---|---|
| Entrez ID | 64854 |
| Gene full name | ubiquitin specific peptidase 46 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001662 | Behavioral fear response | IEA | biological_process |
| GO:0004221 | Ubiquitin thiolesterase activity | IDA IEA | molecular_function |
| GO:0004843 | Ubiquitin-specific protease activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | IEA | biological_process |
| GO:0007610 | Behavior | ISS | biological_process |
| GO:0016579 | Protein deubiquitination | IDA | biological_process |
| GO:0032228 | Regulation of synaptic transmission, GABAergic | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4430757532 | 0.1788417385 | 0.9999902473 | 0.8188021221 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1665223655 |
| GSE13712_SHEAR | Down | -0.0221853782 |
| GSE13712_STATIC | Up | 0.0586141030 |
| GSE19018 | Down | -0.4884194593 |
| GSE19899_A1 | Up | 0.2240737288 |
| GSE19899_A2 | Down | -0.0758998893 |
| PubMed_21979375_A1 | Up | 0.2782678377 |
| PubMed_21979375_A2 | Up | 0.5044846159 |
| GSE35957 | Up | 0.3804746421 |
| GSE36640 | Up | 0.5908290924 |
| GSE54402 | Down | -0.4209667314 |
| GSE9593 | Up | 0.0270236426 |
| GSE43922 | Up | 0.4438321362 |
| GSE24585 | Down | -0.4282267187 |
| GSE37065 | Up | 0.0210473765 |
| GSE28863_A1 | Down | -0.1856800275 |
| GSE28863_A2 | Down | -0.1409606215 |
| GSE28863_A3 | Down | -0.6877175632 |
| GSE28863_A4 | Down | -0.0747516248 |
| GSE48662 | Down | -0.4873918282 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019851 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-106b-5p | MIMAT0000680 | MIRT020484 | Microarray | Functional MTI (Weak) | 17242205 |
| hsa-miR-140-3p | MIMAT0004597 | MIRT038649 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-145-5p | MIMAT0000437 | NA | hsa-miR-145 | 19915607 |
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