HCSGD entry for USP46


1. General information

Official gene symbolUSP46
Entrez ID64854
Gene full nameubiquitin specific peptidase 46
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001662Behavioral fear responseIEAbiological_process
GO:0004221Ubiquitin thiolesterase activityIDA IEAmolecular_function
GO:0004843Ubiquitin-specific protease activityIDAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0006511Ubiquitin-dependent protein catabolic processIEAbiological_process
GO:0007610BehaviorISSbiological_process
GO:0016579Protein deubiquitinationIDAbiological_process
GO:0032228Regulation of synaptic transmission, GABAergicISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.44307575320.17884173850.99999024730.8188021221

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1665223655
GSE13712_SHEARDown-0.0221853782
GSE13712_STATICUp0.0586141030
GSE19018Down-0.4884194593
GSE19899_A1Up0.2240737288
GSE19899_A2Down-0.0758998893
PubMed_21979375_A1Up0.2782678377
PubMed_21979375_A2Up0.5044846159
GSE35957Up0.3804746421
GSE36640Up0.5908290924
GSE54402Down-0.4209667314
GSE9593Up0.0270236426
GSE43922Up0.4438321362
GSE24585Down-0.4282267187
GSE37065Up0.0210473765
GSE28863_A1Down-0.1856800275
GSE28863_A2Down-0.1409606215
GSE28863_A3Down-0.6877175632
GSE28863_A4Down-0.0747516248
GSE48662Down-0.4873918282

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-375MIMAT0000728MIRT019851MicroarrayFunctional MTI (Weak)20215506
hsa-miR-106b-5pMIMAT0000680MIRT020484MicroarrayFunctional MTI (Weak)17242205
hsa-miR-140-3pMIMAT0004597MIRT038649CLASHFunctional MTI (Weak)23622248
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  • mirRecord

MicroRNA name

mirBase ID

Target site number

MiRNA mature ID

Test method inter

MiRNA regulation site

Reporter target site

Pubmed ID

hsa-miR-145-5pMIMAT0000437NAhsa-miR-14519915607
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6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.