HCSGD entry for ISL2
1. General information
| Official gene symbol | ISL2 |
|---|---|
| Entrez ID | 64843 |
| Gene full name | ISL LIM homeobox 2 |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | ISS | molecular_function |
| GO:0003700 | Sequence-specific DNA binding transcription factor activity | IEA | molecular_function |
| GO:0005634 | Nucleus | IC | cellular_component |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0021520 | Spinal cord motor neuron cell fate specification | IEA | biological_process |
| GO:0021524 | Visceral motor neuron differentiation | IEA | biological_process |
| GO:0031290 | Retinal ganglion cell axon guidance | IEA | biological_process |
| GO:0043565 | Sequence-specific DNA binding | IEA | molecular_function |
| GO:0045665 | Negative regulation of neuron differentiation | IEA | biological_process |
| GO:0048666 | Neuron development | TAS | biological_process |
| GO:0048935 | Peripheral nervous system neuron development | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.4794686980 | 0.5918550093 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0402345518 |
| GSE13712_SHEAR | Up | 0.4142949224 |
| GSE13712_STATIC | Down | -0.0143087100 |
| GSE19018 | Up | 0.2694415620 |
| GSE19899_A1 | Down | -0.0860493043 |
| GSE19899_A2 | Down | -0.2257948880 |
| PubMed_21979375_A1 | Down | -0.1345084261 |
| PubMed_21979375_A2 | Up | 0.1405846924 |
| GSE35957 | Down | -0.2820909827 |
| GSE36640 | Down | -0.0117712483 |
| GSE54402 | Down | -0.0291973129 |
| GSE9593 | Up | 0.1337716559 |
| GSE43922 | Up | 0.0536135262 |
| GSE24585 | Down | -0.5432195489 |
| GSE37065 | Down | -0.0720511714 |
| GSE28863_A1 | Down | -0.0419652991 |
| GSE28863_A2 | Up | 0.0465670707 |
| GSE28863_A3 | Up | 0.4169293969 |
| GSE28863_A4 | Up | 0.0615881087 |
| GSE48662 | Up | 0.0971909962 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
