HCSGD entry for GNPNAT1
1. General information
| Official gene symbol | GNPNAT1 |
|---|---|
| Entrez ID | 64841 |
| Gene full name | glucosamine-phosphate N-acetyltransferase 1 |
| Other gene symbols | GNPNAT Gpnat1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0001889 | Liver development | IEA | biological_process |
| GO:0004343 | Glucosamine 6-phosphate N-acetyltransferase activity | IEA TAS | molecular_function |
| GO:0005770 | Late endosome | IEA | cellular_component |
| GO:0005793 | Endoplasmic reticulum-Golgi intermediate compartment | IEA | cellular_component |
| GO:0005794 | Golgi apparatus | IEA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0006041 | Glucosamine metabolic process | IEA | biological_process |
| GO:0006044 | N-acetylglucosamine metabolic process | IEA | biological_process |
| GO:0006048 | UDP-N-acetylglucosamine biosynthetic process | IEA TAS | biological_process |
| GO:0006488 | Dolichol-linked oligosaccharide biosynthetic process | TAS | biological_process |
| GO:0010008 | Endosome membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | TAS | biological_process |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
| GO:0048029 | Monosaccharide binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0927333612 | 0.2669109114 | 0.6389619895 | 0.9890025176 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2587459765 |
| GSE13712_SHEAR | Up | 0.1157043208 |
| GSE13712_STATIC | Up | 0.0901931136 |
| GSE19018 | Down | -0.3245843038 |
| GSE19899_A1 | Up | 0.2602646887 |
| GSE19899_A2 | Up | 0.3212859928 |
| PubMed_21979375_A1 | Up | 0.5497866938 |
| PubMed_21979375_A2 | Up | 0.5786100117 |
| GSE35957 | Down | -0.8297583395 |
| GSE36640 | Down | -0.5202712562 |
| GSE54402 | Up | 0.3577988595 |
| GSE9593 | Down | -0.1653576240 |
| GSE43922 | Up | 0.3116955936 |
| GSE24585 | Down | -0.4978036231 |
| GSE37065 | Down | -0.0293180862 |
| GSE28863_A1 | Down | -0.0936353898 |
| GSE28863_A2 | Down | -0.0632155534 |
| GSE28863_A3 | Down | -0.6649613092 |
| GSE28863_A4 | Up | 0.5770192929 |
| GSE48662 | Down | -0.0199344546 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT001366 | pSILAC//Proteomics;Other | Functional MTI (Weak) | 18668040 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020656 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-331-3p | MIMAT0000760 | MIRT043385 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049476 | CLASH | Functional MTI (Weak) | 23622248 |
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