HCSGD entry for TBC1D15
1. General information
| Official gene symbol | TBC1D15 |
|---|---|
| Entrez ID | 64786 |
| Gene full name | TBC1 domain family, member 15 |
| Other gene symbols | RAB7-GAP |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005097 | Rab GTPase activator activity | IEA ISS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005576 | Extracellular region | IEA | cellular_component |
| GO:0005737 | Cytoplasm | ISS | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0032313 | Regulation of Rab GTPase activity | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0551698758 | 0.6635071388 | 0.5117883222 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2431497448 |
| GSE13712_SHEAR | Down | -0.7050154964 |
| GSE13712_STATIC | Down | -0.6447438727 |
| GSE19018 | Up | 0.8418393412 |
| GSE19899_A1 | Up | 0.4014638307 |
| GSE19899_A2 | Up | 0.1556742392 |
| PubMed_21979375_A1 | Up | 0.2053600226 |
| PubMed_21979375_A2 | Up | 0.1863454092 |
| GSE35957 | Up | 0.2122588299 |
| GSE36640 | Up | 0.3171274744 |
| GSE54402 | Up | 0.1317225497 |
| GSE9593 | Up | 0.1986188395 |
| GSE43922 | Down | -0.0349540678 |
| GSE24585 | Up | 0.2769744707 |
| GSE37065 | Up | 0.1703766322 |
| GSE28863_A1 | Up | 0.2749012837 |
| GSE28863_A2 | Up | 0.4495505019 |
| GSE28863_A3 | Down | -0.6055991413 |
| GSE28863_A4 | Up | 0.1079238961 |
| GSE48662 | Down | -0.2674849263 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-let-7b-5p | MIMAT0000063 | MIRT032446 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT041974 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-5p | MIMAT0000075 | MIRT050522 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050825 | CLASH | Functional MTI (Weak) | 23622248 |
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