HCSGD entry for TBC1D15


1. General information

Official gene symbolTBC1D15
Entrez ID64786
Gene full nameTBC1 domain family, member 15
Other gene symbolsRAB7-GAP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005097Rab GTPase activator activityIEA ISSmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005737CytoplasmISScellular_component
GO:0005739MitochondrionIEAcellular_component
GO:0032313Regulation of Rab GTPase activityISSbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.05516987580.66350713880.51178832221.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2431497448
GSE13712_SHEARDown-0.7050154964
GSE13712_STATICDown-0.6447438727
GSE19018Up0.8418393412
GSE19899_A1Up0.4014638307
GSE19899_A2Up0.1556742392
PubMed_21979375_A1Up0.2053600226
PubMed_21979375_A2Up0.1863454092
GSE35957Up0.2122588299
GSE36640Up0.3171274744
GSE54402Up0.1317225497
GSE9593Up0.1986188395
GSE43922Down-0.0349540678
GSE24585Up0.2769744707
GSE37065Up0.1703766322
GSE28863_A1Up0.2749012837
GSE28863_A2Up0.4495505019
GSE28863_A3Down-0.6055991413
GSE28863_A4Up0.1079238961
GSE48662Down-0.2674849263

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-let-7b-5pMIMAT0000063MIRT032446ProteomicsFunctional MTI (Weak)18668040
hsa-miR-484MIMAT0002174MIRT041974CLASHFunctional MTI (Weak)23622248
hsa-miR-20a-5pMIMAT0000075MIRT050522CLASHFunctional MTI (Weak)23622248
hsa-miR-17-5pMIMAT0000070MIRT050825CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.