HCSGD entry for SI
1. General information
| Official gene symbol | SI |
|---|---|
| Entrez ID | 6476 |
| Gene full name | sucrase-isomaltase (alpha-glucosidase) |
| Other gene symbols | |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004558 | Alpha-glucosidase activity | TAS | molecular_function |
| GO:0004574 | Oligo-1,6-glucosidase activity | IEA | molecular_function |
| GO:0004575 | Sucrose alpha-glucosidase activity | TAS | molecular_function |
| GO:0005794 | Golgi apparatus | TAS | cellular_component |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005903 | Brush border | TAS | cellular_component |
| GO:0005975 | Carbohydrate metabolic process | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0016324 | Apical plasma membrane | IEA | cellular_component |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0044245 | Polysaccharide digestion | TAS | biological_process |
| GO:0044281 | Small molecule metabolic process | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6805387941 | 0.7915422438 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1386694068 |
| GSE13712_SHEAR | Down | -0.1656885021 |
| GSE13712_STATIC | Down | -0.1221174519 |
| GSE19018 | Down | -0.0237099938 |
| GSE19899_A1 | Up | 0.2339064095 |
| GSE19899_A2 | Down | -0.1300547489 |
| PubMed_21979375_A1 | Up | 0.2012329831 |
| PubMed_21979375_A2 | Down | -0.0738082765 |
| GSE35957 | Up | 0.0851873719 |
| GSE36640 | Up | 0.0996640969 |
| GSE54402 | Up | 0.0699928653 |
| GSE9593 | Up | 0.0168801456 |
| GSE43922 | Up | 0.0173392023 |
| GSE24585 | Up | 0.1605923255 |
| GSE37065 | Down | -0.0102395785 |
| GSE28863_A1 | Down | -0.0047623522 |
| GSE28863_A2 | Up | 0.0950907259 |
| GSE28863_A3 | Up | 0.0388114110 |
| GSE28863_A4 | Down | -0.0708611662 |
| GSE48662 | Down | -0.0835265081 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Acarbose | DB00284 | APRD00656 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT030316 | Microarray | Functional MTI (Weak) | 19088304 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 1733257 | Sucrase-isomaltase gene expression along crypt-villus axis of human small intestine is regulated at level of mRNA abundance |
| 1733257 | Sucrase-isomaltase (SI) is an enterocyte-specific, brush-border enzyme that has little activity in crypt cells and maximal activity in low and mid villus cells |
Entries Per Page
Displaying Page of
