HCSGD entry for TNS3
1. General information
| Official gene symbol | TNS3 |
|---|---|
| Entrez ID | 64759 |
| Gene full name | tensin 3 |
| Other gene symbols | TEM6 TENS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005925 | Focal adhesion | IEA | cellular_component |
| GO:0008284 | Positive regulation of cell proliferation | IEA | biological_process |
| GO:0016477 | Cell migration | IEA | biological_process |
| GO:0035556 | Intracellular signal transduction | IEA | biological_process |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
| GO:0048286 | Lung alveolus development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0945259679 | 0.1317079404 | 0.6440636811 | 0.6994924738 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0434853827 |
| GSE13712_SHEAR | Up | 0.8273007430 |
| GSE13712_STATIC | Up | 0.6459101168 |
| GSE19018 | Down | -0.1422047210 |
| GSE19899_A1 | Down | -0.5163646044 |
| GSE19899_A2 | Down | -0.1388764346 |
| PubMed_21979375_A1 | Down | -0.7857224788 |
| PubMed_21979375_A2 | Down | -0.0774724652 |
| GSE35957 | Up | 0.1800955410 |
| GSE36640 | Up | 0.0680777834 |
| GSE54402 | Down | -0.1798176066 |
| GSE9593 | Up | 0.4768258522 |
| GSE43922 | Down | -0.6018882729 |
| GSE24585 | Up | 0.0356317902 |
| GSE37065 | Up | 0.3621197032 |
| GSE28863_A1 | Up | 0.5593963329 |
| GSE28863_A2 | Up | 0.5819262913 |
| GSE28863_A3 | Down | -0.0163363543 |
| GSE28863_A4 | Down | -0.5204594887 |
| GSE48662 | Up | 0.7696753326 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019755 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030755 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043688 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7i-5p | MIMAT0000415 | MIRT046548 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
