HCSGD entry for MARC1
1. General information
| Official gene symbol | MARC1 |
|---|---|
| Entrez ID | 64757 |
| Gene full name | mitochondrial amidoxime reducing component 1 |
| Other gene symbols | MOSC1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003824 | Catalytic activity | IEA | molecular_function |
| GO:0005739 | Mitochondrion | ISS | cellular_component |
| GO:0005741 | Mitochondrial outer membrane | IEA | cellular_component |
| GO:0005743 | Mitochondrial inner membrane | IEA | cellular_component |
| GO:0008940 | Nitrate reductase activity | IDA | molecular_function |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0030151 | Molybdenum ion binding | IDA IEA | molecular_function |
| GO:0030170 | Pyridoxal phosphate binding | IEA | molecular_function |
| GO:0042126 | Nitrate metabolic process | IDA | biological_process |
| GO:0043546 | Molybdopterin cofactor binding | IDA | molecular_function |
| GO:0051410 | Detoxification of nitrogen compound | NAS | biological_process |
| GO:0055114 | Oxidation-reduction process | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9841746058 | 0.0318583299 | 0.9999902473 | 0.3355728800 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0242895906 |
| GSE13712_SHEAR | Down | -0.0648810149 |
| GSE13712_STATIC | Down | -0.3533539788 |
| GSE19018 | Down | -0.2673832814 |
| GSE19899_A1 | Up | 0.0419525065 |
| GSE19899_A2 | Down | -0.2917055553 |
| PubMed_21979375_A1 | Down | -0.1596088206 |
| PubMed_21979375_A2 | Down | -0.2247407912 |
| GSE35957 | Down | -0.2012734217 |
| GSE36640 | Down | -0.6123849377 |
| GSE54402 | Down | -0.6725653945 |
| GSE9593 | Down | -1.2345982742 |
| GSE43922 | Down | -0.0827839190 |
| GSE24585 | Down | -0.3255811202 |
| GSE37065 | Down | -0.3011701862 |
| GSE28863_A1 | Down | -0.0317636418 |
| GSE28863_A2 | Up | 0.2202845893 |
| GSE28863_A3 | Up | 0.1433782965 |
| GSE28863_A4 | Up | 0.0542610243 |
| GSE48662 | Down | -0.2037074947 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT001536 | pSILAC//Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048573 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
