HCSGD entry for SMYD3


1. General information

Official gene symbolSMYD3
Entrez ID64754
Gene full nameSET and MYND domain containing 3
Other gene symbolsKMT3E ZMYND1 ZNFN3A1 bA74P14.1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0018022Peptidyl-lysine methylationISSbiological_process
GO:0018024Histone-lysine N-methyltransferase activityIEA ISSmolecular_function
GO:0046872Metal ion bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.03605447740.21948537290.43165363310.9016816763

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0440218795
GSE13712_SHEARDown-0.2517887263
GSE13712_STATICUp0.0718111989
GSE19018Up0.6180261586
GSE19899_A1Up0.6043693564
GSE19899_A2Up0.1616665275
PubMed_21979375_A1Up0.1506199603
PubMed_21979375_A2Up0.6576642997
GSE35957Up1.8976083888
GSE36640Down-0.2979406362
GSE54402Up0.0317596023
GSE9593Up0.2340824454
GSE43922Up0.5900458002
GSE24585Down-0.0597571773
GSE37065Down-0.7934345762
GSE28863_A1Down-0.4424620524
GSE28863_A2Up0.4204998812
GSE28863_A3Down-0.2030715797
GSE28863_A4Down-0.3071743915
GSE48662Down-0.4793144731

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT004725Luciferase reporter assay//qRT-PCR//Western blotFunctional MTI19843643
hsa-miR-124-3pMIMAT0000422MIRT004725Luciferase reporter assayFunctional MTI22819820
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.