HCSGD entry for PDIA2
1. General information
| Official gene symbol | PDIA2 |
|---|---|
| Entrez ID | 64714 |
| Gene full name | protein disulfide isomerase family A, member 2 |
| Other gene symbols | PDA2 PDI PDIP PDIR |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003756 | Protein disulfide isomerase activity | IEA | molecular_function |
| GO:0005496 | Steroid binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005783 | Endoplasmic reticulum | TAS | cellular_component |
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0006457 | Protein folding | TAS | biological_process |
| GO:0006621 | Protein retention in ER lumen | TAS | biological_process |
| GO:0006662 | Glycerol ether metabolic process | IEA | biological_process |
| GO:0015035 | Protein disulfide oxidoreductase activity | IEA | molecular_function |
| GO:0016853 | Isomerase activity | IEA | molecular_function |
| GO:0045454 | Cell redox homeostasis | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8349658410 | 0.7042887010 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0246098672 |
| GSE13712_SHEAR | Down | -0.1039027487 |
| GSE13712_STATIC | Down | -0.0783521540 |
| GSE19018 | Up | 0.0881168662 |
| GSE19899_A1 | Up | 0.0628110237 |
| GSE19899_A2 | Up | 0.0313302928 |
| PubMed_21979375_A1 | Down | -0.0074847721 |
| PubMed_21979375_A2 | Down | -0.1614561563 |
| GSE35957 | Up | 0.0793540961 |
| GSE36640 | Down | -0.0323248659 |
| GSE54402 | Down | -0.0582707987 |
| GSE9593 | Down | -0.0031330848 |
| GSE43922 | Up | 0.0109649588 |
| GSE24585 | Up | 0.0881653442 |
| GSE37065 | Down | -0.0385886123 |
| GSE28863_A1 | Down | -0.1785433998 |
| GSE28863_A2 | Down | -0.0447754586 |
| GSE28863_A3 | Up | 0.3812119668 |
| GSE28863_A4 | Up | 0.1022380699 |
| GSE48662 | Down | -0.1060053220 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
