HCSGD entry for TMPRSS3


1. General information

Official gene symbolTMPRSS3
Entrez ID64699
Gene full nametransmembrane protease, serine 3
Other gene symbolsDFNB10 DFNB8 ECHOS1 TADG12
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004252Serine-type endopeptidase activityIEA NASmolecular_function
GO:0005044Scavenger receptor activityIEAmolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0006508ProteolysisIEA NASbiological_process
GO:0006883Cellular sodium ion homeostasisIDAbiological_process
GO:0007605Sensory perception of soundIEAbiological_process
GO:0016020MembraneIEAcellular_component
GO:0016021Integral component of membraneNAScellular_component
GO:0017080Sodium channel regulator activityIDAmolecular_function
GO:0043025Neuronal cell bodyIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83256367920.85845371000.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0049945329
GSE13712_SHEARDown-0.0406764232
GSE13712_STATICDown-0.0873852129
GSE19018Up0.0508585658
GSE19899_A1Up0.0640518360
GSE19899_A2Down-0.0764017852
PubMed_21979375_A1Up0.0292433786
PubMed_21979375_A2Down-0.0377849283
GSE35957Up0.0714346132
GSE36640Up0.0683136740
GSE54402Down-0.0254603843
GSE9593Up0.0432341886
GSE43922Up0.1294161126
GSE24585Up0.0815635181
GSE37065Up0.0176542276
GSE28863_A1Down-0.0865563297
GSE28863_A2Down-0.1544140433
GSE28863_A3Up0.2318485116
GSE28863_A4Up0.0149307546
GSE48662Up0.0161709265

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.