HCSGD entry for FBXW4
1. General information
| Official gene symbol | FBXW4 |
|---|---|
| Entrez ID | 6468 |
| Gene full name | F-box and WD repeat domain containing 4 |
| Other gene symbols | DAC FBW4 FBWD4 SHFM3 SHSF3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000151 | Ubiquitin ligase complex | NAS | cellular_component |
| GO:0002053 | Positive regulation of mesenchymal cell proliferation | IEA | biological_process |
| GO:0003674 | Molecular_function | ND | molecular_function |
| GO:0006511 | Ubiquitin-dependent protein catabolic process | NAS | biological_process |
| GO:0016055 | Wnt signaling pathway | IEA | biological_process |
| GO:0030326 | Embryonic limb morphogenesis | NAS | biological_process |
| GO:0042733 | Embryonic digit morphogenesis | IEA | biological_process |
| GO:0051216 | Cartilage development | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2031268607 | 0.7195226891 | 0.8701306816 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0825063387 |
| GSE13712_SHEAR | Down | -0.1852182989 |
| GSE13712_STATIC | Down | -0.0075902720 |
| GSE19018 | Down | -0.2140580862 |
| GSE19899_A1 | Down | -0.1855040038 |
| GSE19899_A2 | Up | 0.3145652741 |
| PubMed_21979375_A1 | Up | 0.0952362664 |
| PubMed_21979375_A2 | Up | 0.3950143190 |
| GSE35957 | Up | 0.2601047880 |
| GSE36640 | Up | 0.2830863977 |
| GSE54402 | Up | 0.0767809315 |
| GSE9593 | Up | 0.5894962364 |
| GSE43922 | Down | -0.1064452233 |
| GSE24585 | Up | 0.3242640457 |
| GSE37065 | Down | -0.0012899283 |
| GSE28863_A1 | Up | 0.0291535371 |
| GSE28863_A2 | Down | -0.2543575960 |
| GSE28863_A3 | Up | 0.1929813312 |
| GSE28863_A4 | Down | -0.0155798892 |
| GSE48662 | Up | 0.5419522965 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
