HCSGD entry for ALDH8A1
1. General information
| Official gene symbol | ALDH8A1 |
|---|---|
| Entrez ID | 64577 |
| Gene full name | aldehyde dehydrogenase 8 family, member A1 |
| Other gene symbols | ALDH12 DJ352A20.2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001758 | Retinal dehydrogenase activity | IDA | molecular_function |
| GO:0005622 | Intracellular | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0016620 | Oxidoreductase activity, acting on the aldehyde or oxo group of donors, NAD or NADP as acceptor | IEA | molecular_function |
| GO:0042573 | Retinoic acid metabolic process | IDA | biological_process |
| GO:0042574 | Retinal metabolic process | IDA | biological_process |
| GO:0042904 | 9-cis-retinoic acid biosynthetic process | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0093506820 | 0.9852191558 | 0.2476049296 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8289154279 |
| GSE13712_SHEAR | Up | 0.3202667958 |
| GSE13712_STATIC | Up | 0.4992139439 |
| GSE19018 | Up | 0.1332469353 |
| GSE19899_A1 | Up | 0.2635477371 |
| GSE19899_A2 | Up | 1.9107590669 |
| PubMed_21979375_A1 | Up | 1.0766805970 |
| PubMed_21979375_A2 | Up | 1.5818213896 |
| GSE35957 | Down | -0.1552596683 |
| GSE36640 | Up | 0.5158289136 |
| GSE54402 | Down | -0.0251077384 |
| GSE9593 | Down | -0.1230024937 |
| GSE43922 | Up | 0.0686303222 |
| GSE24585 | Down | -0.0034493214 |
| GSE37065 | Down | -0.0139553916 |
| GSE28863_A1 | Up | 0.0166206370 |
| GSE28863_A2 | Up | 0.3598064186 |
| GSE28863_A3 | Up | 0.0902504787 |
| GSE28863_A4 | Up | 0.0560231703 |
| GSE48662 | Up | 0.2030146720 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-335-5p | MIMAT0000765 | MIRT018613 | Microarray | Functional MTI (Weak) | 18185580 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
