HCSGD entry for DCLRE1C
1. General information
| Official gene symbol | DCLRE1C |
|---|---|
| Entrez ID | 64421 |
| Gene full name | DNA cross-link repair 1C |
| Other gene symbols | A-SCID DCLREC1C RS-SCID SCIDA SNM1C hSNM1C |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000014 | Single-stranded DNA endodeoxyribonuclease activity | IDA | molecular_function |
| GO:0000723 | Telomere maintenance | IEA | biological_process |
| GO:0000737 | DNA catabolic process, endonucleolytic | IDA | biological_process |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006302 | Double-strand break repair | IEA | biological_process |
| GO:0006308 | DNA catabolic process | IDA | biological_process |
| GO:0006310 | DNA recombination | IEA | biological_process |
| GO:0008409 | 5'-3' exonuclease activity | IDA | molecular_function |
| GO:0010212 | Response to ionizing radiation | IEA | biological_process |
| GO:0030183 | B cell differentiation | IEA | biological_process |
| GO:0090305 | Nucleic acid phosphodiester bond hydrolysis | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9401525702 | 0.0614920976 | 0.9999902473 | 0.4672440820 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1474968626 |
| GSE13712_SHEAR | Up | 0.0836405141 |
| GSE13712_STATIC | Down | -0.1196804243 |
| GSE19018 | Down | -0.1601993082 |
| GSE19899_A1 | Down | -0.3095191160 |
| GSE19899_A2 | Down | -0.7328558981 |
| PubMed_21979375_A1 | Up | 0.0560509110 |
| PubMed_21979375_A2 | Down | -0.4897383527 |
| GSE35957 | Down | -0.6356079832 |
| GSE36640 | Down | -1.0677871961 |
| GSE54402 | Up | 0.1136316636 |
| GSE9593 | Down | -0.3829482477 |
| GSE43922 | Down | -0.0851714502 |
| GSE24585 | Up | 0.0058294488 |
| GSE37065 | Up | 0.1100704272 |
| GSE28863_A1 | Up | 0.1782976758 |
| GSE28863_A2 | Up | 0.1970882673 |
| GSE28863_A3 | Down | -0.2293677153 |
| GSE28863_A4 | Down | -0.0913217704 |
| GSE48662 | Down | -0.1131912675 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-324-3p | MIMAT0000762 | MIRT042846 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
