HCSGD entry for HHIP

1. General information

Official gene symbolHHIP
Entrez ID64399
Gene full namehedgehog interacting protein
Other gene symbolsHIP
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005887Integral component of plasma membraneISScellular_component
GO:0005975Carbohydrate metabolic processIEAbiological_process
GO:0007224Smoothened signaling pathwayIEAbiological_process
GO:0007405Neuroblast proliferationIEAbiological_process
GO:0008270Zinc ion bindingIDAmolecular_function
GO:0009953Dorsal/ventral pattern formationIEAbiological_process
GO:0009968Negative regulation of signal transductionIDAbiological_process
GO:0009986Cell surfaceIEAcellular_component
GO:0016901Oxidoreductase activity, acting on the CH-OH group of donors, quinone or similar compound as acceptorIEAmolecular_function
GO:0040036Regulation of fibroblast growth factor receptor signaling pathwayIEAbiological_process
GO:0045879Negative regulation of smoothened signaling pathwayISSbiological_process
GO:0048038Quinone bindingIEAmolecular_function
GO:0048705Skeletal system morphogenesisISSbiological_process
GO:0060441Epithelial tube branching involved in lung morphogenesisIEAbiological_process
GO:0097108Hedgehog family protein bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.46555139240.00050670190.99999024730.0414189441

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2384492311
GSE13712_SHEARDown-0.3847752245
GSE13712_STATICDown-0.6486706574
GSE19018Up0.6419697220
GSE19899_A1Down-0.8593527822
GSE19899_A2Down-0.8454815066
PubMed_21979375_A1Down-3.0511250727
PubMed_21979375_A2Down-2.7294796080
GSE35957Down-0.6531914602
GSE36640Down-5.4635384430
GSE54402Down-1.6567464285
GSE9593Down-0.3862949555
GSE43922Down-1.6056469320
GSE24585Up0.2312776857
GSE37065Up0.2326090167
GSE28863_A1Down-0.0515258598
GSE28863_A2Up0.0049271797
GSE28863_A3Up0.2450963064
GSE28863_A4Up0.5203790245
GSE48662Down-1.3764502699

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.