HCSGD entry for MPP5
1. General information
| Official gene symbol | MPP5 |
|---|---|
| Entrez ID | 64398 |
| Gene full name | membrane protein, palmitoylated 5 (MAGUK p55 subfamily member 5) |
| Other gene symbols | PALS1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005886 | Plasma membrane | IEA TAS | cellular_component |
| GO:0005923 | Tight junction | IEA | cellular_component |
| GO:0012505 | Endomembrane system | IEA | cellular_component |
| GO:0019904 | Protein domain specific binding | IPI | molecular_function |
| GO:0032287 | Peripheral nervous system myelin maintenance | IEA | biological_process |
| GO:0032288 | Myelin assembly | IEA | biological_process |
| GO:0034329 | Cell junction assembly | TAS | biological_process |
| GO:0035749 | Myelin sheath adaxonal region | IEA | cellular_component |
| GO:0035750 | Protein localization to myelin sheath abaxonal region | IEA | biological_process |
| GO:0043219 | Lateral loop | IEA | cellular_component |
| GO:0043220 | Schmidt-Lanterman incisure | IEA | cellular_component |
| GO:0043234 | Protein complex | IEA | cellular_component |
| GO:0045216 | Cell-cell junction organization | TAS | biological_process |
| GO:0070830 | Tight junction assembly | TAS | biological_process |
| GO:0090002 | Establishment of protein localization to plasma membrane | IEA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3311622621 | 0.1313803845 | 0.9999902473 | 0.6983748384 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.3230041319 |
| GSE13712_SHEAR | Up | 0.3424249679 |
| GSE13712_STATIC | Up | 0.3832580697 |
| GSE19018 | Up | 0.4187484751 |
| GSE19899_A1 | Down | -0.8437412631 |
| GSE19899_A2 | Up | 0.0295232881 |
| PubMed_21979375_A1 | Down | -0.6072184889 |
| PubMed_21979375_A2 | Down | -0.1073143974 |
| GSE35957 | Up | 0.2787450148 |
| GSE36640 | Up | 0.3456311008 |
| GSE54402 | Down | -0.0920715395 |
| GSE9593 | Up | 0.3628311328 |
| GSE43922 | Down | -0.6569022720 |
| GSE24585 | Down | -0.1357702731 |
| GSE37065 | Up | 0.0756435096 |
| GSE28863_A1 | Down | -0.4169240319 |
| GSE28863_A2 | Down | -0.2380906999 |
| GSE28863_A3 | Down | -0.7079030590 |
| GSE28863_A4 | Up | 0.2179561109 |
| GSE48662 | Down | -0.0795186783 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019954 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020290 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-155-5p | MIMAT0000646 | MIRT020854 | Reporter assay;Other | Functional MTI | 20584899 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025870 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-148a-3p | MIMAT0000243 | MIRT025990 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026647 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030917 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-93-3p | MIMAT0004509 | MIRT038797 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
