HCSGD entry for GREM2
1. General information
| Official gene symbol | GREM2 |
|---|---|
| Entrez ID | 64388 |
| Gene full name | gremlin 2, DAN family BMP antagonist |
| Other gene symbols | CKTSF1B2 DAND3 PRDC |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005125 | Cytokine activity | IEA | molecular_function |
| GO:0005576 | Extracellular region | TAS | cellular_component |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0008201 | Heparin binding | ISS | molecular_function |
| GO:0010172 | Embryonic body morphogenesis | ISS | biological_process |
| GO:0019221 | Cytokine-mediated signaling pathway | ISS | biological_process |
| GO:0030509 | BMP signaling pathway | TAS | biological_process |
| GO:0060300 | Regulation of cytokine activity | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.8919466358 | 0.0004443904 | 0.9999902473 | 0.0389893333 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -1.2825680652 |
| GSE13712_SHEAR | Up | 0.0677042215 |
| GSE13712_STATIC | Up | 0.1335923320 |
| GSE19018 | Down | -2.9434011735 |
| GSE19899_A1 | Down | -0.9261749260 |
| GSE19899_A2 | Down | -2.4941612594 |
| PubMed_21979375_A1 | Down | -3.2390108763 |
| PubMed_21979375_A2 | Down | -3.5383080118 |
| GSE35957 | Up | 0.7953019994 |
| GSE36640 | Up | 0.9003835465 |
| GSE54402 | Down | -0.2361419539 |
| GSE9593 | Down | -0.3731676732 |
| GSE43922 | Down | -1.0432879210 |
| GSE24585 | Up | 0.0324562111 |
| GSE37065 | Up | 0.5738249881 |
| GSE28863_A1 | Down | -0.0270017160 |
| GSE28863_A2 | Down | -0.3700105329 |
| GSE28863_A3 | Down | -0.2136994201 |
| GSE28863_A4 | Down | -0.3260518280 |
| GSE48662 | Down | -0.1255262079 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029946 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
