HCSGD entry for RFWD2
1. General information
| Official gene symbol | RFWD2 |
|---|---|
| Entrez ID | 64326 |
| Gene full name | ring finger and WD repeat domain 2, E3 ubiquitin protein ligase |
| Other gene symbols | COP1 RNF200 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000139 | Golgi membrane | IEA | cellular_component |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005813 | Centrosome | IDA | cellular_component |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005925 | Focal adhesion | IDA | cellular_component |
| GO:0006977 | DNA damage response, signal transduction by p53 class mediator resulting in cell cycle arrest | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0016567 | Protein ubiquitination | IEA | biological_process |
| GO:0016607 | Nuclear speck | IEA | cellular_component |
| GO:0016874 | Ligase activity | IEA | molecular_function |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9035997455 | 0.3739589035 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2234966076 |
| GSE13712_SHEAR | Down | -0.2504594521 |
| GSE13712_STATIC | Down | -0.1906743248 |
| GSE19018 | Up | 0.1364160058 |
| GSE19899_A1 | Down | -0.1844715701 |
| GSE19899_A2 | Down | -0.2147149345 |
| PubMed_21979375_A1 | Up | 0.0302740548 |
| PubMed_21979375_A2 | Down | -0.0363409393 |
| GSE35957 | Down | -0.0817749375 |
| GSE36640 | Down | -0.3018078397 |
| GSE54402 | Up | 0.2364098813 |
| GSE9593 | Down | -0.1196319630 |
| GSE43922 | Down | -0.0321440024 |
| GSE24585 | Up | 0.1435036186 |
| GSE37065 | Up | 0.1003319326 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Down | -0.4289955452 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-24-3p | MIMAT0000080 | MIRT030609 | Microarray | Functional MTI (Weak) | 19748357 |
| hsa-miR-1180-3p | MIMAT0005825 | MIRT035914 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
