HCSGD entry for SOX17

1. General information

Official gene symbolSOX17
Entrez ID64321
Gene full nameSRY (sex determining region Y)-box 17
Other gene symbolsVUR3
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000122Negative regulation of transcription from RNA polymerase II promoterIEAbiological_process
GO:0001525AngiogenesisISSbiological_process
GO:0001570VasculogenesisISSbiological_process
GO:0001706Endoderm formationIDAbiological_process
GO:0001828Inner cell mass cellular morphogenesisIEAbiological_process
GO:0001947Heart loopingISSbiological_process
GO:0003142Cardiogenic plate morphogenesisISSbiological_process
GO:0003143Embryonic heart tube morphogenesisISSbiological_process
GO:0003151Outflow tract morphogenesisISSbiological_process
GO:0003308Negative regulation of Wnt signaling pathway involved in heart developmentIEAbiological_process
GO:0003705RNA polymerase II distal enhancer sequence-specific DNA binding transcription factor activityISSmolecular_function
GO:0003713Transcription coactivator activityIEAmolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005667Transcription factor complexIDAcellular_component
GO:0006355Regulation of transcription, DNA-templatedISSbiological_process
GO:0007283SpermatogenesisIEAbiological_process
GO:0007493Endodermal cell fate determinationIEAbiological_process
GO:0008013Beta-catenin bindingIPImolecular_function
GO:0008134Transcription factor bindingIPImolecular_function
GO:0021903Rostrocaudal neural tube patterningIEAbiological_process
GO:0023019Signal transduction involved in regulation of gene expressionIEAbiological_process
GO:0030308Negative regulation of cell growthIMPbiological_process
GO:0031648Protein destabilizationIMPbiological_process
GO:0035050Embryonic heart tube developmentISSbiological_process
GO:0042074Cell migration involved in gastrulationIEAbiological_process
GO:0042662Negative regulation of mesodermal cell fate specificationIEAbiological_process
GO:0042789MRNA transcription from RNA polymerase II promoterIDAbiological_process
GO:0043565Sequence-specific DNA bindingIEAmolecular_function
GO:0044212Transcription regulatory region DNA bindingISSmolecular_function
GO:0045597Positive regulation of cell differentiationIEAbiological_process
GO:0045732Positive regulation of protein catabolic processIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedISSbiological_process
GO:0045944Positive regulation of transcription from RNA polymerase II promoterIDAbiological_process
GO:0045995Regulation of embryonic developmentISSbiological_process
GO:0048617Embryonic foregut morphogenesisISSbiological_process
GO:0048643Positive regulation of skeletal muscle tissue developmentIEAbiological_process
GO:0048866Stem cell fate specificationIEAbiological_process
GO:0050821Protein stabilizationIMPbiological_process
GO:0060070Canonical Wnt signaling pathwayIEAbiological_process
GO:0060214Endocardium formationISSbiological_process
GO:0060807Regulation of transcription from RNA polymerase II promoter involved in definitive endodermal cell fate specificationISSbiological_process
GO:0060913Cardiac cell fate determinationIMPbiological_process
GO:0060914Heart formationTASbiological_process
GO:0060956Endocardial cell differentiationISSbiological_process
GO:0061009Common bile duct developmentIEAbiological_process
GO:0061010Gall bladder developmentIEAbiological_process
GO:0061031Endodermal digestive tract morphogenesisISSbiological_process
GO:0072001Renal system developmentIMPbiological_process
GO:0072091Regulation of stem cell proliferationIEAbiological_process
GO:0090090Negative regulation of canonical Wnt signaling pathwayIMPbiological_process
GO:2000035Regulation of stem cell divisionIEAbiological_process
GO:2000043Regulation of cardiac cell fate specificationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00510479840.83551865050.18669722221.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up1.8980414629
GSE13712_SHEARDown-0.7382224012
GSE13712_STATICDown-1.2264778738
GSE19018Down-0.0644308467
GSE19899_A1Up0.3384019845
GSE19899_A2Up1.2345430496
PubMed_21979375_A1Up0.8383998564
PubMed_21979375_A2Up2.6173459227
GSE35957Up0.2333467207
GSE36640Down-0.0006191694
GSE54402Up3.9059489334
GSE9593Down-0.0161777494
GSE43922Up0.0663466614
GSE24585Up0.1216799900
GSE37065Down-0.0368339232
GSE28863_A1Down-0.0919295997
GSE28863_A2Up0.1154805304
GSE28863_A3Up0.3328003832
GSE28863_A4Up0.1124961912
GSE48662Down-0.0641521265

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.