HCSGD entry for SRSF7
1. General information
| Official gene symbol | SRSF7 |
|---|---|
| Entrez ID | 6432 |
| Gene full name | serine/arginine-rich splicing factor 7 |
| Other gene symbols | 9G8 AAG3 SFRS7 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000166 | Nucleotide binding | IEA | molecular_function |
| GO:0000398 | MRNA splicing, via spliceosome | TAS | biological_process |
| GO:0003676 | Nucleic acid binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0006366 | Transcription from RNA polymerase II promoter | TAS | biological_process |
| GO:0006369 | Termination of RNA polymerase II transcription | TAS | biological_process |
| GO:0006397 | MRNA processing | TAS | biological_process |
| GO:0006406 | MRNA export from nucleus | TAS | biological_process |
| GO:0008270 | Zinc ion binding | IEA | molecular_function |
| GO:0008380 | RNA splicing | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0031124 | MRNA 3'-end processing | TAS | biological_process |
| GO:0048025 | Negative regulation of mRNA splicing, via spliceosome | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9966247483 | 0.0039642339 | 0.9999902473 | 0.1281476829 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.3363196532 |
| GSE13712_SHEAR | Up | 0.0119283206 |
| GSE13712_STATIC | Down | -0.1956588316 |
| GSE19018 | Down | -1.0948311885 |
| GSE19899_A1 | Down | -0.4414170852 |
| GSE19899_A2 | Down | -0.7197626516 |
| PubMed_21979375_A1 | Down | -0.5024710059 |
| PubMed_21979375_A2 | Down | -0.6334022928 |
| GSE35957 | Down | -0.5156466608 |
| GSE36640 | Down | -1.0064499653 |
| GSE54402 | Down | -0.1235397649 |
| GSE9593 | Down | -0.4987009618 |
| GSE43922 | Down | -0.2672946634 |
| GSE24585 | Down | -0.4436488462 |
| GSE37065 | Down | -0.0651309257 |
| GSE28863_A1 | Up | 0.0771807674 |
| GSE28863_A2 | Up | 0.3117383566 |
| GSE28863_A3 | Down | -0.3015847223 |
| GSE28863_A4 | Down | -0.0949500908 |
| GSE48662 | Down | -0.7303197734 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-374b-5p | MIMAT0004955 | MIRT016062 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-421 | MIMAT0003339 | MIRT016101 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-130b-3p | MIMAT0000691 | MIRT020279 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-1 | MIMAT0000416 | MIRT023916 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025199 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-22-3p | MIMAT0000077 | MIRT030646 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-19b-3p | MIMAT0000074 | MIRT031228 | Sequencing | Functional MTI (Weak) | 20371350 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
