HCSGD entry for SRSF5


1. General information

Official gene symbolSRSF5
Entrez ID6430
Gene full nameserine/arginine-rich splicing factor 5
Other gene symbolsHRS SFRS5 SRP40
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000166Nucleotide bindingIEAmolecular_function
GO:0000398MRNA splicing, via spliceosomeTASbiological_process
GO:0003676Nucleic acid bindingIEAmolecular_function
GO:0003723RNA bindingIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005634NucleusIDAcellular_component
GO:0005654NucleoplasmTAScellular_component
GO:0005730NucleolusIDAcellular_component
GO:0005737CytoplasmIDAcellular_component
GO:0006366Transcription from RNA polymerase II promoterTASbiological_process
GO:0006369Termination of RNA polymerase II transcriptionTASbiological_process
GO:0006376MRNA splice site selectionTASbiological_process
GO:0006397MRNA processingTASbiological_process
GO:0006406MRNA export from nucleusTASbiological_process
GO:0008380RNA splicingTASbiological_process
GO:0009611Response to woundingIEAbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0016607Nuclear speckIEA ISScellular_component
GO:0031124MRNA 3'-end processingTASbiological_process
GO:0050733RS domain bindingIEAmolecular_function
GO:0051726Regulation of cell cycleIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.14270138670.82228446490.75728275931.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0152441142
GSE13712_SHEARUp0.2258439556
GSE13712_STATICDown-0.1738967537
GSE19018Down-0.2120070111
GSE19899_A1Up0.1755949082
GSE19899_A2Up0.0538871622
PubMed_21979375_A1Down-0.0440806583
PubMed_21979375_A2Down-0.0851018143
GSE35957Up0.4735960608
GSE36640Down-0.1222538884
GSE54402Up0.1243725299
GSE9593Down-0.0632456873
GSE43922Up0.0781845535
GSE24585Up0.4696735504
GSE37065Up0.0375807578
GSE28863_A1Up0.4669249479
GSE28863_A2Up0.0939815575
GSE28863_A3Down-0.4357704774
GSE28863_A4Up0.3375814136
GSE48662Up0.0051960253

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT023067Proteomics;MicroarrayNon-Functional MTI (Weak)18668037
hsa-miR-1MIMAT0000416MIRT024020ProteomicsFunctional MTI (Weak)18668040
hsa-miR-1236-3pMIMAT0005591MIRT036252CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049180CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.