HCSGD entry for RHBDF1

1. General information

Official gene symbolRHBDF1
Entrez ID64285
Gene full namerhomboid 5 homolog 1 (Drosophila)
Other gene symbolsC16orf8 Dist1 EGFR-RS gene-89 gene-90 hDist1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000139Golgi membraneIDAcellular_component
GO:0004252Serine-type endopeptidase activityIDA IEAmolecular_function
GO:0005789Endoplasmic reticulum membraneIDAcellular_component
GO:0006508ProteolysisIEAbiological_process
GO:0008283Cell proliferationIMPbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0016021Integral component of membraneIEAcellular_component
GO:0016477Cell migrationIMPbiological_process
GO:0019838Growth factor bindingIEAmolecular_function
GO:0042058Regulation of epidermal growth factor receptor signaling pathwayIMPbiological_process
GO:0050708Regulation of protein secretionIMPbiological_process
GO:0050709Negative regulation of protein secretionIDAbiological_process
GO:0061136Regulation of proteasomal protein catabolic processIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00170219980.99731373430.11035369461.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.4798231743
GSE13712_SHEARUp0.8433913834
GSE13712_STATICUp0.4438368040
GSE19018Up0.1903640978
GSE19899_A1Up1.1310490986
GSE19899_A2Up0.8281666576
PubMed_21979375_A1Up1.3869796582
PubMed_21979375_A2Up1.4390065176
GSE35957Up0.0755683666
GSE36640Up0.6622429555
GSE54402Up0.4167809440
GSE9593Up0.3578855853
GSE43922Up1.2111595456
GSE24585Up0.1346602183
GSE37065Up0.0526900642
GSE28863_A1Up0.3035489168
GSE28863_A2Up0.1048688727
GSE28863_A3Up0.0573116043
GSE28863_A4Up0.0133208852
GSE48662Down-0.0201077506

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-124-3pMIMAT0000422MIRT022709MicroarrayFunctional MTI (Weak)18668037
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.