HCSGD entry for PDLIM2


1. General information

Official gene symbolPDLIM2
Entrez ID64236
Gene full namePDZ and LIM domain 2 (mystique)
Other gene symbolsMYSTIQUE SLIM
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005634NucleusIEAcellular_component
GO:0005737CytoplasmIEAcellular_component
GO:0005925Focal adhesionIDAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0015629Actin cytoskeletonIDAcellular_component
GO:0031005Filamin bindingIEAmolecular_function
GO:0032036Myosin heavy chain bindingIEAmolecular_function
GO:0051371Muscle alpha-actinin bindingIEAmolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.82211728660.06702413660.99999024730.4884114895

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.3449398480
GSE13712_SHEARDown-0.2292876510
GSE13712_STATICUp0.0488440662
GSE19018Up0.5727404052
GSE19899_A1Down-0.4562388019
GSE19899_A2Down-0.1781115470
PubMed_21979375_A1Down-0.7209267887
PubMed_21979375_A2Down-0.2557178661
GSE35957Up0.1926742104
GSE36640Up0.3054903226
GSE54402Down-0.6361359699
GSE9593Up0.2935320061
GSE43922Down-0.2669333300
GSE24585Down-0.0347059329
GSE37065Down-0.3515000112
GSE28863_A1Down-0.0947178462
GSE28863_A2Down-0.1765246110
GSE28863_A3Up0.1232021562
GSE28863_A4Down-0.0760690176
GSE48662Up0.3710120682

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-484MIMAT0002174MIRT041815CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.