HCSGD entry for ATL2
1. General information
| Official gene symbol | ATL2 |
|---|---|
| Entrez ID | 64225 |
| Gene full name | atlastin GTPase 2 |
| Other gene symbols | ARL3IP2 ARL6IP2 atlastin2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003924 | GTPase activity | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | IEA | cellular_component |
| GO:0006184 | GTP catabolic process | NAS | biological_process |
| GO:0006888 | ER to Golgi vesicle-mediated transport | IMP | biological_process |
| GO:0007029 | Endoplasmic reticulum organization | IMP | biological_process |
| GO:0007030 | Golgi organization | IMP | biological_process |
| GO:0008152 | Metabolic process | NAS | biological_process |
| GO:0016021 | Integral component of membrane | IDA | cellular_component |
| GO:0042802 | Identical protein binding | IDA | molecular_function |
| GO:0051260 | Protein homooligomerization | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2101202348 | 0.2591423426 | 0.8833479246 | 0.9762439531 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1593105762 |
| GSE13712_SHEAR | Up | 0.2995055449 |
| GSE13712_STATIC | Down | -0.0000436152 |
| GSE19018 | Down | -0.1517000793 |
| GSE19899_A1 | Up | 0.0979539145 |
| GSE19899_A2 | Down | -0.0635406498 |
| PubMed_21979375_A1 | Up | 1.1831305800 |
| PubMed_21979375_A2 | Up | 0.9886630480 |
| GSE35957 | Down | -0.0989536879 |
| GSE36640 | Down | -0.6881771611 |
| GSE54402 | Down | -0.0510958197 |
| GSE9593 | Down | -0.3854178650 |
| GSE43922 | Up | 0.4293420776 |
| GSE24585 | Down | -0.3266495759 |
| GSE37065 | Up | 0.1346590180 |
| GSE28863_A1 | Down | -0.1088781070 |
| GSE28863_A2 | Up | 0.6857416080 |
| GSE28863_A3 | Down | -0.7013032421 |
| GSE28863_A4 | Down | -0.1552012983 |
| GSE48662 | Down | -0.1222367670 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-155-5p | MIMAT0000646 | MIRT020733 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-186-5p | MIMAT0000456 | MIRT021152 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-125a-5p | MIMAT0000443 | MIRT021317 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT024158 | Sequencing | Functional MTI (Weak) | 20371350 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT028540 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT031714 | Proteomics | Functional MTI (Weak) | 18668040 |
| hsa-miR-484 | MIMAT0002174 | MIRT042321 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
