HCSGD entry for MLST8

1. General information

Official gene symbolMLST8
Entrez ID64223
Gene full nameMTOR associated protein, LST8 homolog (S. cerevisiae)
Other gene symbolsGBL GbetaL LST8 POP3 WAT1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmISScellular_component
GO:0005829CytosolTAScellular_component
GO:0007173Epidermal growth factor receptor signaling pathwayTASbiological_process
GO:0008286Insulin receptor signaling pathwayTASbiological_process
GO:0008543Fibroblast growth factor receptor signaling pathwayTASbiological_process
GO:0030838Positive regulation of actin filament polymerizationIEAbiological_process
GO:0031295T cell costimulationTASbiological_process
GO:0032008Positive regulation of TOR signalingIMPbiological_process
GO:0032314Regulation of Rac GTPase activityIEAbiological_process
GO:0032956Regulation of actin cytoskeleton organizationIMPbiological_process
GO:0038095Fc-epsilon receptor signaling pathwayTASbiological_process
GO:0045087Innate immune responseTASbiological_process
GO:0048011Neurotrophin TRK receptor signaling pathwayTASbiological_process
GO:0048015Phosphatidylinositol-mediated signalingTASbiological_process
GO:0050731Positive regulation of peptidyl-tyrosine phosphorylationIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.11277033550.63061534900.69205595711.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.2240143294
GSE13712_SHEARDown-0.2765966334
GSE13712_STATICDown-0.3582958315
GSE19018Up0.1623204880
GSE19899_A1Up0.0291630871
GSE19899_A2Up0.3315589512
PubMed_21979375_A1Up1.1919146184
PubMed_21979375_A2Up1.4939536957
GSE35957Down-0.0113982869
GSE36640Down-0.0706159136
GSE54402Up0.2347668818
GSE9593Up0.0596580113
GSE43922Up0.1378328710
GSE24585Down-0.4402425466
GSE37065Down-0.0878115837
GSE28863_A1Down-0.0980566970
GSE28863_A2Down-0.1451704222
GSE28863_A3Up0.0274902415
GSE28863_A4Up0.0142302252
GSE48662Up0.3360672804

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-4326MIMAT0016888MIRT052837CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.