HCSGD entry for PJA1


1. General information

Official gene symbolPJA1
Entrez ID64219
Gene full namepraja ring finger 1, E3 ubiquitin protein ligase
Other gene symbolsPRAJA1 RNF70
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004842Ubiquitin-protein ligase activityIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005737CytoplasmIEAcellular_component
GO:0008270Zinc ion bindingIEAmolecular_function
GO:0030163Protein catabolic processIEAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.83023971730.16233967930.99999024730.7783726594

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1745322884
GSE13712_SHEARDown-0.5848258115
GSE13712_STATICDown-0.2048371962
GSE19018Down-0.2851239865
GSE19899_A1Down-0.1699112177
GSE19899_A2Up0.1271565808
PubMed_21979375_A1Up0.1004299556
PubMed_21979375_A2Down-0.1525896146
GSE35957Down-0.1621173194
GSE36640Up0.4101939680
GSE54402Down-0.1324454544
GSE9593Down-0.3617259492
GSE43922Up0.0511601718
GSE24585Down-0.3149482246
GSE37065Down-0.1167376407
GSE28863_A1Up0.3055169243
GSE28863_A2Down-0.0411989060
GSE28863_A3Down-0.3438843232
GSE28863_A4Up0.1205339547
GSE48662Up0.0338237221

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.