HCSGD entry for TFB2M
1. General information
| Official gene symbol | TFB2M |
|---|---|
| Entrez ID | 64216 |
| Gene full name | transcription factor B2, mitochondrial |
| Other gene symbols | Hkp1 mtTFB2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000179 | RRNA (adenine-N6,N6-)-dimethyltransferase activity | IEA | molecular_function |
| GO:0003712 | Transcription cofactor activity | IDA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005759 | Mitochondrial matrix | IDA TAS | cellular_component |
| GO:0006390 | Transcription from mitochondrial promoter | IDA TAS | biological_process |
| GO:0006391 | Transcription initiation from mitochondrial promoter | IDA TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0042645 | Mitochondrial nucleoid | IDA | cellular_component |
| GO:0045893 | Positive regulation of transcription, DNA-templated | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.6880146119 | 0.3069271456 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0718223917 |
| GSE13712_SHEAR | Up | 0.0893429378 |
| GSE13712_STATIC | Up | 0.1063070221 |
| GSE19018 | Down | -0.2403707098 |
| GSE19899_A1 | Up | 0.0450666015 |
| GSE19899_A2 | Up | 0.2607834898 |
| PubMed_21979375_A1 | Up | 0.4005545723 |
| PubMed_21979375_A2 | Up | 0.2132305804 |
| GSE35957 | Up | 0.0679122288 |
| GSE36640 | Down | -0.2926893831 |
| GSE54402 | Up | 0.2362994042 |
| GSE9593 | Down | -0.0160663882 |
| GSE43922 | Up | 0.0561273523 |
| GSE24585 | Down | -0.6702874879 |
| GSE37065 | Down | -0.1410471674 |
| GSE28863_A1 | Up | 0.0742990369 |
| GSE28863_A2 | Up | 0.2057626288 |
| GSE28863_A3 | Down | -0.5363639164 |
| GSE28863_A4 | Down | -0.1740217710 |
| GSE48662 | Down | -0.5003105057 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-124-3p | MIMAT0000422 | MIRT022454 | Proteomics;Microarray | Functional MTI (Weak) | 18668037 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029159 | Microarray | Functional MTI (Weak) | 19088304 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
