HCSGD entry for DPEP3
1. General information
| Official gene symbol | DPEP3 |
|---|---|
| Entrez ID | 64180 |
| Gene full name | dipeptidase 3 |
| Other gene symbols | MBD3 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0006508 | Proteolysis | IEA | biological_process |
| GO:0007140 | Male meiosis | ISS | biological_process |
| GO:0008235 | Metalloexopeptidase activity | IEA | molecular_function |
| GO:0008239 | Dipeptidyl-peptidase activity | IEA | molecular_function |
| GO:0016805 | Dipeptidase activity | IEA | molecular_function |
| GO:0031225 | Anchored component of membrane | IEA | cellular_component |
| GO:0046872 | Metal ion binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1613146385 | 0.9294719312 | 0.7951285153 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.1498796061 |
| GSE13712_SHEAR | Down | -0.0755661564 |
| GSE13712_STATIC | Down | -0.0338484327 |
| GSE19018 | Up | 0.1483555131 |
| GSE19899_A1 | Up | 0.1057094556 |
| GSE19899_A2 | Up | 0.0878500809 |
| PubMed_21979375_A1 | Down | -0.0948609347 |
| PubMed_21979375_A2 | Up | 0.0484642308 |
| GSE35957 | Up | 0.2535353087 |
| GSE36640 | Down | -0.0370497775 |
| GSE54402 | Down | -0.0771233261 |
| GSE9593 | Down | -0.0618320469 |
| GSE43922 | Up | 0.1030022356 |
| GSE24585 | Up | 0.0924665668 |
| GSE37065 | Down | -0.0745306378 |
| GSE28863_A1 | Down | -0.1344058012 |
| GSE28863_A2 | Up | 0.0548851022 |
| GSE28863_A3 | Up | 0.2849183126 |
| GSE28863_A4 | Up | 0.0892080917 |
| GSE48662 | Up | 1.7878751152 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 25481090 | In addition, the protein levels of p-AKT, p-ERK, Bcl-2, matrix metallopeptidase 9 (MMP-9) and fibronectin (FN) were significantly reduced following quercetin treatment |
| 24964749 | The inhibition of ERCC1 by siRNA increased the expression of matrix metallopeptidase 13 and decreased collagen type II |
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