HCSGD entry for SET
1. General information
| Official gene symbol | SET |
|---|---|
| Entrez ID | 6418 |
| Gene full name | SET nuclear oncogene |
| Other gene symbols | 2PP2A I2PP2A IGAAD IPP2A2 PHAPII TAF-I TAF-IBETA |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0004864 | Protein phosphatase inhibitor activity | TAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA IEA | cellular_component |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005829 | Cytosol | IEA | cellular_component |
| GO:0006260 | DNA replication | TAS | biological_process |
| GO:0006334 | Nucleosome assembly | IEA | biological_process |
| GO:0006337 | Nucleosome disassembly | TAS | biological_process |
| GO:0006913 | Nucleocytoplasmic transport | NAS | biological_process |
| GO:0008601 | Protein phosphatase type 2A regulator activity | TAS | molecular_function |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0035067 | Negative regulation of histone acetylation | TAS | biological_process |
| GO:0042393 | Histone binding | TAS | molecular_function |
| GO:0043086 | Negative regulation of catalytic activity | TAS | biological_process |
| GO:0043234 | Protein complex | IDA | cellular_component |
| GO:0043524 | Negative regulation of neuron apoptotic process | IGI | biological_process |
| GO:0045892 | Negative regulation of transcription, DNA-templated | IDA | biological_process |
| GO:0048471 | Perinuclear region of cytoplasm | IDA | cellular_component |
| GO:0050790 | Regulation of catalytic activity | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9671790471 | 0.0588832301 | 0.9999902473 | 0.4568681108 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2081400321 |
| GSE13712_SHEAR | Down | -0.2952770832 |
| GSE13712_STATIC | Down | -0.1889681841 |
| GSE19018 | Down | -0.3324102760 |
| GSE19899_A1 | Down | -0.4645325649 |
| GSE19899_A2 | Down | -0.5485571176 |
| PubMed_21979375_A1 | Down | -0.3542063300 |
| PubMed_21979375_A2 | Down | -0.6875613316 |
| GSE35957 | Down | -0.3535468698 |
| GSE36640 | Down | -0.8190174983 |
| GSE54402 | Up | 0.0533900211 |
| GSE9593 | Down | -0.0893936375 |
| GSE43922 | - | - |
| GSE24585 | - | - |
| GSE37065 | - | - |
| GSE28863_A1 | Up | 0.1346542301 |
| GSE28863_A2 | Down | -0.0696955752 |
| GSE28863_A3 | Down | -0.0188711490 |
| GSE28863_A4 | Up | 0.1636428338 |
| GSE48662 | Down | -0.0712694398 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-199b-5p | MIMAT0000263 | MIRT001112 | qRT-PCR//Western blot//Luciferase reporter assay | Functional MTI | 19900756 |
| hsa-miR-375 | MIMAT0000728 | MIRT019832 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-122-5p | MIMAT0000421 | MIRT023293 | Proteomics | Functional MTI (Weak) | 21750653 |
| hsa-miR-877-3p | MIMAT0004950 | MIRT036919 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-505-5p | MIMAT0004776 | MIRT037978 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038454 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-18a-3p | MIMAT0002891 | MIRT040796 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT041853 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-423-3p | MIMAT0001340 | MIRT042555 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-378a-5p | MIMAT0000731 | MIRT044003 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-185-5p | MIMAT0000455 | MIRT045377 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048527 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-93-5p | MIMAT0000093 | MIRT048741 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-26a-5p | MIMAT0000082 | MIRT050146 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-1260b | MIMAT0015041 | MIRT052765 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-199b-5p | MIMAT0000263 | NA | hsa-miR-199b-5p | {Western blot} | {overexpression} | 19900756 |
Entries Per Page
Displaying Page of
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
