HCSGD entry for RRAGC
1. General information
| Official gene symbol | RRAGC |
|---|---|
| Entrez ID | 64121 |
| Gene full name | Ras-related GTP binding C |
| Other gene symbols | GTR2 RAGC TIB929 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000287 | Magnesium ion binding | NAS | molecular_function |
| GO:0003924 | GTPase activity | IDA | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005525 | GTP binding | IDA | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0005764 | Lysosome | IDA | cellular_component |
| GO:0006184 | GTP catabolic process | IDA | biological_process |
| GO:0006351 | Transcription, DNA-templated | NAS | biological_process |
| GO:0006915 | Apoptotic process | NAS | biological_process |
| GO:0007264 | Small GTPase mediated signal transduction | TAS | biological_process |
| GO:0008380 | RNA splicing | NAS | biological_process |
| GO:0016049 | Cell growth | NAS | biological_process |
| GO:0019003 | GDP binding | IDA | molecular_function |
| GO:0034613 | Cellular protein localization | ISS | biological_process |
| GO:0046982 | Protein heterodimerization activity | IPI | molecular_function |
| GO:0071230 | Cellular response to amino acid stimulus | ISS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0090007902 | 0.9601551841 | 0.2422390593 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.8651446194 |
| GSE13712_SHEAR | Up | 0.2908644914 |
| GSE13712_STATIC | Up | 0.1339497494 |
| GSE19018 | Up | 0.1265324552 |
| GSE19899_A1 | Up | 0.5175298616 |
| GSE19899_A2 | Up | 0.5074726984 |
| PubMed_21979375_A1 | Down | -0.1053648143 |
| PubMed_21979375_A2 | Up | 0.5828002935 |
| GSE35957 | Down | -0.0366592765 |
| GSE36640 | Up | 0.5827658780 |
| GSE54402 | Up | 0.2864839254 |
| GSE9593 | Up | 0.8098738969 |
| GSE43922 | Up | 0.2191287157 |
| GSE24585 | Up | 0.1572208024 |
| GSE37065 | Up | 0.0228423775 |
| GSE28863_A1 | Up | 0.2842486706 |
| GSE28863_A2 | Up | 1.5032519920 |
| GSE28863_A3 | Down | -0.4554396336 |
| GSE28863_A4 | Down | -0.2581303202 |
| GSE48662 | Down | -0.4874948075 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019727 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT028929 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030696 | Microarray | Functional MTI (Weak) | 18591254 |
| hsa-miR-29a-3p | MIMAT0000086 | MIRT049975 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051496 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
