HCSGD entry for MOAP1
1. General information
| Official gene symbol | MOAP1 |
|---|---|
| Entrez ID | 64112 |
| Gene full name | modulator of apoptosis 1 |
| Other gene symbols | MAP-1 PNMA4 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0006919 | Activation of cysteine-type endopeptidase activity involved in apoptotic process | IDA | biological_process |
| GO:0006921 | Cellular component disassembly involved in execution phase of apoptosis | IDA | biological_process |
| GO:0030262 | Apoptotic nuclear changes | IDA | biological_process |
| GO:0042803 | Protein homodimerization activity | IPI | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0017838228 | 0.9977151856 | 0.1123130952 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2806237302 |
| GSE13712_SHEAR | Up | 0.0895781214 |
| GSE13712_STATIC | Down | -0.0295772335 |
| GSE19018 | Up | 0.3471368869 |
| GSE19899_A1 | Up | 1.1444346631 |
| GSE19899_A2 | Up | 1.3710987760 |
| PubMed_21979375_A1 | Up | 0.5859586981 |
| PubMed_21979375_A2 | Up | 0.8372858863 |
| GSE35957 | Up | 0.5859592252 |
| GSE36640 | Up | 1.8691290336 |
| GSE54402 | Up | 0.3018950740 |
| GSE9593 | Up | 0.3980821948 |
| GSE43922 | Up | 0.6384065134 |
| GSE24585 | Up | 0.2482272113 |
| GSE37065 | Up | 0.1875465749 |
| GSE28863_A1 | Up | 0.0521803360 |
| GSE28863_A2 | Up | 0.2324514153 |
| GSE28863_A3 | Up | 0.0518238081 |
| GSE28863_A4 | Up | 0.2909957164 |
| GSE48662 | Up | 0.0585322153 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1228-3p | MIMAT0005583 | MIRT006333 | qRT-PCR//Western blot | Functional MTI | 22434376 |
| hsa-miR-215-5p | MIMAT0000272 | MIRT024361 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-192-5p | MIMAT0000222 | MIRT026155 | Microarray | Functional MTI (Weak) | 19074876 |
| hsa-miR-21-5p | MIMAT0000076 | MIRT030749 | Microarray | Functional MTI (Weak) | 18591254 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 3956580 | On staining with a monoclonal antibody raised against microtubule-associated protein-1 (MAP-1), dot-like structures were seen in the nuclei of interphase cells, but not in those of non-cycling G0-arrested cells |
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