HCSGD entry for SELL
1. General information
| Official gene symbol | SELL |
|---|---|
| Entrez ID | 6402 |
| Gene full name | selectin L |
| Other gene symbols | CD62L LAM1 LECAM1 LEU8 LNHR LSEL LYAM1 PLNHR TQ1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0002020 | Protease binding | IPI | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005886 | Plasma membrane | TAS | cellular_component |
| GO:0005887 | Integral component of plasma membrane | TAS | cellular_component |
| GO:0007155 | Cell adhesion | IEA | biological_process |
| GO:0007596 | Blood coagulation | TAS | biological_process |
| GO:0008201 | Heparin binding | TAS | molecular_function |
| GO:0009897 | External side of plasma membrane | IEA | cellular_component |
| GO:0030246 | Carbohydrate binding | IEA | molecular_function |
| GO:0033198 | Response to ATP | IEA | biological_process |
| GO:0043208 | Glycosphingolipid binding | TAS | molecular_function |
| GO:0050776 | Regulation of immune response | TAS | biological_process |
| GO:0050839 | Cell adhesion molecule binding | IEA | molecular_function |
| GO:0050900 | Leukocyte migration | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3724784317 | 0.3595584096 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0113855504 |
| GSE13712_SHEAR | Down | -0.4631936337 |
| GSE13712_STATIC | Up | 0.1422316629 |
| GSE19018 | Up | 0.0414252488 |
| GSE19899_A1 | Up | 0.2011748698 |
| GSE19899_A2 | Down | -0.1045439890 |
| PubMed_21979375_A1 | Up | 0.0258741198 |
| PubMed_21979375_A2 | Down | -0.0177896997 |
| GSE35957 | Up | 0.1736320130 |
| GSE36640 | Down | -0.2356083714 |
| GSE54402 | Up | 0.1255131126 |
| GSE9593 | Down | -0.1045836436 |
| GSE43922 | Up | 0.0501028770 |
| GSE24585 | Up | 0.6114174690 |
| GSE37065 | Up | 0.2968665560 |
| GSE28863_A1 | Down | -0.3810909181 |
| GSE28863_A2 | Down | -0.1848002612 |
| GSE28863_A3 | Down | -0.0098274219 |
| GSE28863_A4 | Up | 0.0425077082 |
| GSE48662 | Down | -0.0613051309 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: 2 abstracts the gene occurs.
PubMed ID of the article | Sentenece the gene occurs |
|---|---|
| 17379755 | Blood lymphocytes isolated before, immediately after, and 1 h after exercise were assessed for cell surface expression of KLRG1, CD57, CD28, CD45RA, CD45RO, CD62L, and lymphocyte subset markers (CD3, CD4, CD8, CD56) by flow cytometry |
| 11985666 | We also analysed the expression of naive cell-associated markers, CD28, CD62L and CD45RA/CD62L in T lymphocytes of 47 cynomolgus monkeys |
| 11985666 | The percentage of CD62L+ subsets was significantly decreased with age in both CD4+ (R = - 0 |
| 11985666 | From the comparison of telomere length among PBMC, CD62L+ and CD62L- T lymphocytes, it was clearly evident that loss of naive subsets results in the shortening of telomere length in vivo |
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