HCSGD entry for ELMO2
1. General information
| Official gene symbol | ELMO2 |
|---|---|
| Entrez ID | 63916 |
| Gene full name | engulfment and cell motility 2 |
| Other gene symbols | CED-12 CED12 ELMO-2 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | IDA TAS | cellular_component |
| GO:0005856 | Cytoskeleton | IEA | cellular_component |
| GO:0006909 | Phagocytosis | IEA | biological_process |
| GO:0006915 | Apoptotic process | IEA | biological_process |
| GO:0016020 | Membrane | IDA | cellular_component |
| GO:0017124 | SH3 domain binding | IEA | molecular_function |
| GO:0030971 | Receptor tyrosine kinase binding | IPI | molecular_function |
| GO:0038096 | Fc-gamma receptor signaling pathway involved in phagocytosis | TAS | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0060326 | Cell chemotaxis | IMP | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.1366133164 | 0.9580635994 | 0.7450889142 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0630674482 |
| GSE13712_SHEAR | Up | 0.0313780198 |
| GSE13712_STATIC | Up | 0.0257131553 |
| GSE19018 | Down | -0.0324816841 |
| GSE19899_A1 | Down | -0.1052083462 |
| GSE19899_A2 | Up | 0.3955385777 |
| PubMed_21979375_A1 | Up | 0.4328348991 |
| PubMed_21979375_A2 | Up | 0.2363285829 |
| GSE35957 | Up | 0.1600395653 |
| GSE36640 | Up | 0.5116793847 |
| GSE54402 | Up | 0.1534498220 |
| GSE9593 | Up | 0.3155754741 |
| GSE43922 | Up | 0.0936159200 |
| GSE24585 | Up | 0.2541274766 |
| GSE37065 | Up | 0.3208692270 |
| GSE28863_A1 | Up | 0.0547169551 |
| GSE28863_A2 | Up | 0.0565813493 |
| GSE28863_A3 | Up | 0.0013219117 |
| GSE28863_A4 | Up | 0.0514904073 |
| GSE48662 | Down | -0.0838336297 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT016514 | Microarray | Functional MTI (Weak) | 20304954 |
| hsa-miR-429 | MIMAT0001536 | MIRT016635 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200a-3p | MIMAT0000682 | MIRT020346 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200c-3p | MIMAT0000617 | MIRT021068 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-141-3p | MIMAT0000432 | MIRT021653 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-200b-3p | MIMAT0000318 | MIRT024122 | Reporter assay | Functional MTI | 20005803 |
| hsa-miR-17-5p | MIMAT0000070 | MIRT050992 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-141-3p | MIMAT0000432 | NA | hsa-miR-141 | 20005803 | |||
| hsa-miR-200a-3p | MIMAT0000682 | NA | hsa-miR-200a | 20005803 | |||
| hsa-miR-200b-3p | MIMAT0000318 | NA | hsa-miR-200b | 20005803 | |||
| hsa-miR-429 | MIMAT0001536 | NA | hsa-miR-429 | 20005803 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
