HCSGD entry for SH2D4A
1. General information
| Official gene symbol | SH2D4A |
|---|---|
| Entrez ID | 63898 |
| Gene full name | SH2 domain containing 4A |
| Other gene symbols | PPP1R38 SH2A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005730 | Nucleolus | IDA | cellular_component |
| GO:0005737 | Cytoplasm | IDA | cellular_component |
| GO:0010923 | Negative regulation of phosphatase activity | IDA | biological_process |
| GO:0019902 | Phosphatase binding | IDA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9510198397 | 0.0065235933 | 0.9999902473 | 0.1636646226 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.4315351695 |
| GSE13712_SHEAR | Up | 0.3051600080 |
| GSE13712_STATIC | Up | 0.0655773722 |
| GSE19018 | Down | -0.1513984408 |
| GSE19899_A1 | Down | -0.2364038586 |
| GSE19899_A2 | Down | -0.2480048135 |
| PubMed_21979375_A1 | Down | -1.5502128159 |
| PubMed_21979375_A2 | Down | -0.6836882143 |
| GSE35957 | Up | 0.6470736317 |
| GSE36640 | Down | -1.5275203670 |
| GSE54402 | Down | -0.5536140355 |
| GSE9593 | Up | 0.2399408983 |
| GSE43922 | Down | -0.6842487423 |
| GSE24585 | Down | -0.4023436775 |
| GSE37065 | Down | -0.1463083380 |
| GSE28863_A1 | Down | -0.0459639652 |
| GSE28863_A2 | Down | -0.0835500686 |
| GSE28863_A3 | Up | 0.0427921609 |
| GSE28863_A4 | Down | -0.4459524265 |
| GSE48662 | Down | -0.1011510945 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | MIRT002747 | Microarray | Functional MTI (Weak) | 15685193 |
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- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-1 | MIMAT0000416 | NA | hsa-miR-1 | 15685193 |
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6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
