HCSGD entry for XCL1

1. General information

Official gene symbolXCL1
Entrez ID6375
Gene full namechemokine (C motif) ligand 1
Other gene symbolsATAC LPTN LTN SCM-1 SCM-1a SCM1 SCM1A SCYC1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

color bar
This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001916Positive regulation of T cell mediated cytotoxicityIDAbiological_process
GO:0002690Positive regulation of leukocyte chemotaxisISSbiological_process
GO:0002725Negative regulation of T cell cytokine productionIDAbiological_process
GO:0002726Positive regulation of T cell cytokine productionISSbiological_process
GO:0002826Negative regulation of T-helper 1 type immune responseICbiological_process
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceISScellular_component
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionICbiological_process
GO:0007267Cell-cell signalingIDAbiological_process
GO:0008009Chemokine activityIDAmolecular_function
GO:0009615Response to virusIDAbiological_process
GO:0010820Positive regulation of T cell chemotaxisIDAbiological_process
GO:0030593Neutrophil chemotaxisTASbiological_process
GO:0032689Negative regulation of interferon-gamma productionIDAbiological_process
GO:0032703Negative regulation of interleukin-2 productionIDAbiological_process
GO:0032733Positive regulation of interleukin-10 productionIDAbiological_process
GO:0035782Mature natural killer cell chemotaxisIDAbiological_process
GO:0042379Chemokine receptor bindingIDA NASmolecular_function
GO:0042803Protein homodimerization activityIDAmolecular_function
GO:0043433Negative regulation of sequence-specific DNA binding transcription factor activityIDAbiological_process
GO:0045892Negative regulation of transcription, DNA-templatedIDAbiological_process
GO:0050727Regulation of inflammatory responseIDAbiological_process
GO:0051209Release of sequestered calcium ion into cytosolISSbiological_process
GO:0051281Positive regulation of release of sequestered calcium ion into cytosolIDAbiological_process
GO:0071353Cellular response to interleukin-4ISSbiological_process
GO:0071560Cellular response to transforming growth factor beta stimulusISSbiological_process
GO:0071636Positive regulation of transforming growth factor beta productionIDAbiological_process
GO:0071663Positive regulation of granzyme B productionIDAbiological_process
GO:0090023Positive regulation of neutrophil chemotaxisISSbiological_process
GO:2000412Positive regulation of thymocyte migrationISSbiological_process
GO:2000503Positive regulation of natural killer cell chemotaxisIDAbiological_process
GO:2000513Positive regulation of granzyme A productionIDAbiological_process
GO:2000518Negative regulation of T-helper 1 cell activationIDAbiological_process
GO:2000538Positive regulation of B cell chemotaxisISSbiological_process
GO:2000553Positive regulation of T-helper 2 cell cytokine productionISSbiological_process
GO:2000556Positive regulation of T-helper 1 cell cytokine productionISSbiological_process
GO:2000558Positive regulation of immunoglobulin production in mucosal tissueISSbiological_process
GO:2000562Negative regulation of CD4-positive, alpha-beta T cell proliferationIDAbiological_process
GO:2000563Positive regulation of CD4-positive, alpha-beta T cell proliferationISSbiological_process
GO:2000566Positive regulation of CD8-positive, alpha-beta T cell proliferationIDAbiological_process
Entries Per Page
Displaying Page of

4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.52979309680.92726497470.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0590114102
GSE13712_SHEARUp0.1592050983
GSE13712_STATICDown-0.1169750913
GSE19018Up0.0379715397
GSE19899_A1Up0.0431321875
GSE19899_A2Up0.1303814219
PubMed_21979375_A1Up0.0554637359
PubMed_21979375_A2Up0.1047799366
GSE35957Up0.0519031940
GSE36640Up0.1622801583
GSE54402Down-0.0141758865
GSE9593Up0.0036642631
GSE43922Up0.1134518418
GSE24585Up0.3740785986
GSE37065Down-0.0424080539
GSE28863_A1Down-0.1161782640
GSE28863_A2Down-0.0594309709
GSE28863_A3Down-0.0688192816
GSE28863_A4Up0.1336056477
GSE48662Up0.0336018501

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.