HCSGD entry for CXCL11


1. General information

Official gene symbolCXCL11
Entrez ID6373
Gene full namechemokine (C-X-C motif) ligand 11
Other gene symbolsH174 I-TAC IP-9 IP9 SCYB11 SCYB9B b-R1
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0002690Positive regulation of leukocyte chemotaxisIEAbiological_process
GO:0005515Protein bindingIPImolecular_function
GO:0005576Extracellular regionTAScellular_component
GO:0005615Extracellular spaceIEAcellular_component
GO:0006935ChemotaxisIDAbiological_process
GO:0006954Inflammatory responseIEAbiological_process
GO:0006955Immune responseIEAbiological_process
GO:0007165Signal transductionTASbiological_process
GO:0007267Cell-cell signalingTASbiological_process
GO:0008009Chemokine activityIDAmolecular_function
GO:0008284Positive regulation of cell proliferationIEAbiological_process
GO:0030816Positive regulation of cAMP metabolic processIDAbiological_process
GO:0042127Regulation of cell proliferationIMPbiological_process
GO:0043950Positive regulation of cAMP-mediated signalingIDAbiological_process
GO:0048248CXCR3 chemokine receptor bindingIDAmolecular_function
GO:0051281Positive regulation of release of sequestered calcium ion into cytosolIDAbiological_process
GO:0060326Cell chemotaxisIDA TASbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.00853554200.88792500660.23701782701.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.3360474539
GSE13712_SHEARUp3.3703123257
GSE13712_STATICUp0.9733617892
GSE19018Up0.1102914452
GSE19899_A1Down-0.0097083988
GSE19899_A2Up0.2008233339
PubMed_21979375_A1Up0.5070679259
PubMed_21979375_A2Up0.1115589488
GSE35957Down-1.0643816211
GSE36640Up1.2565200233
GSE54402Up0.1437405459
GSE9593Up0.1520844388
GSE43922Up0.1133389266
GSE24585Up0.5099695948
GSE37065Up1.9122590153
GSE28863_A1Down-0.1555958371
GSE28863_A2Down-0.0674409396
GSE28863_A3Up0.0604383676
GSE28863_A4Down-0.0219011584
GSE48662Down-0.0120204878

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.