HCSGD entry for CCL8
1. General information
| Official gene symbol | CCL8 |
|---|---|
| Entrez ID | 6355 |
| Gene full name | chemokine (C-C motif) ligand 8 |
| Other gene symbols | HC14 MCP-2 MCP2 SCYA10 SCYA8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IDA | molecular_function |
| GO:0005615 | Extracellular space | IEA | cellular_component |
| GO:0006468 | Protein phosphorylation | IDA | biological_process |
| GO:0006816 | Calcium ion transport | IDA | biological_process |
| GO:0006874 | Cellular calcium ion homeostasis | IDA | biological_process |
| GO:0006887 | Exocytosis | IDA | biological_process |
| GO:0006935 | Chemotaxis | TAS | biological_process |
| GO:0006954 | Inflammatory response | IEA | biological_process |
| GO:0006955 | Immune response | IEA | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007267 | Cell-cell signaling | IDA | biological_process |
| GO:0008009 | Chemokine activity | IEA | molecular_function |
| GO:0008152 | Metabolic process | IDA | biological_process |
| GO:0008201 | Heparin binding | IEA | molecular_function |
| GO:0009615 | Response to virus | TAS | biological_process |
| GO:0016004 | Phospholipase activator activity | IDA | molecular_function |
| GO:0016310 | Phosphorylation | IDA | biological_process |
| GO:0043085 | Positive regulation of catalytic activity | IDA | biological_process |
| GO:0050790 | Regulation of catalytic activity | IDA | biological_process |
| GO:0060326 | Cell chemotaxis | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.0228453858 | 0.8408678128 | 0.3606136091 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2803122259 |
| GSE13712_SHEAR | Down | -0.4508812820 |
| GSE13712_STATIC | Down | -0.1721783121 |
| GSE19018 | Up | 0.4353274802 |
| GSE19899_A1 | Up | 0.1524513600 |
| GSE19899_A2 | Up | 0.3404766232 |
| PubMed_21979375_A1 | Up | 0.2824410449 |
| PubMed_21979375_A2 | Up | 0.1186264056 |
| GSE35957 | Up | 0.1288124762 |
| GSE36640 | Up | 0.0522473535 |
| GSE54402 | Up | 0.0243336194 |
| GSE9593 | Up | 0.3619174859 |
| GSE43922 | Up | 0.0569325672 |
| GSE24585 | Up | 0.3153703411 |
| GSE37065 | Up | 0.7933460628 |
| GSE28863_A1 | Up | 0.7179716398 |
| GSE28863_A2 | Up | 0.9410640061 |
| GSE28863_A3 | Up | 0.0971557981 |
| GSE28863_A4 | Down | -0.1173759803 |
| GSE48662 | Down | -0.0868468233 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Pyroglutamic Acid | DB03088 | EXPT00247 |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-23a-3p | MIMAT0000078 | MIRT050431 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
MicroRNA name | mirBase ID | Target site number | MiRNA mature ID | Test method inter | MiRNA regulation site | Reporter target site | Pubmed ID |
|---|---|---|---|---|---|---|---|
| hsa-miR-146a-5p | MIMAT0000449 | 1 | hsa-miR-146a | {ELISA} | {overexpression} | 20181935 |
Entries Per Page
Displaying Page of
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
