HCSGD entry for SCN7A
1. General information
| Official gene symbol | SCN7A |
|---|---|
| Entrez ID | 6332 |
| Gene full name | sodium channel, voltage-gated, type VII, alpha subunit |
| Other gene symbols | NaG Nav2.1 Nav2.2 SCN6A |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0001518 | Voltage-gated sodium channel complex | IEA | cellular_component |
| GO:0005216 | Ion channel activity | IEA | molecular_function |
| GO:0005248 | Voltage-gated sodium channel activity | IEA | molecular_function |
| GO:0005272 | Sodium channel activity | IEA | molecular_function |
| GO:0005886 | Plasma membrane | IEA | cellular_component |
| GO:0006814 | Sodium ion transport | TAS | biological_process |
| GO:0006936 | Muscle contraction | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0055078 | Sodium ion homeostasis | IEA | biological_process |
| GO:0097386 | Glial cell projection | IEA | cellular_component |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3419867178 | 0.0927978116 | 0.9999902473 | 0.5800820988 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.2217156918 |
| GSE13712_SHEAR | Down | -0.0698760130 |
| GSE13712_STATIC | Up | 0.0559598090 |
| GSE19018 | Down | -1.9188022348 |
| GSE19899_A1 | Up | 0.0945764873 |
| GSE19899_A2 | Down | -0.9036942125 |
| PubMed_21979375_A1 | Up | 0.3522346627 |
| PubMed_21979375_A2 | Up | 0.4153875022 |
| GSE35957 | Up | 0.2844454012 |
| GSE36640 | Down | -0.3589389369 |
| GSE54402 | Down | -2.0143702539 |
| GSE9593 | Down | -0.0871841724 |
| GSE43922 | Down | -0.2304750005 |
| GSE24585 | Up | 1.1313843110 |
| GSE37065 | Up | 0.0168946200 |
| GSE28863_A1 | Up | 0.0106556624 |
| GSE28863_A2 | Up | 0.1606085725 |
| GSE28863_A3 | Up | 0.0728118946 |
| GSE28863_A4 | Up | 0.0446107359 |
| GSE48662 | Up | 0.0307443270 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
- MicroRNAs
- mirTarBase
No target information from mirTarBase
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
