HCSGD entry for SCN2B

1. General information

Official gene symbolSCN2B
Entrez ID6327
Gene full namesodium channel, voltage-gated, type II, beta subunit
Other gene symbols
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0001518Voltage-gated sodium channel complexIDA TAScellular_component
GO:0007268Synaptic transmissionTASbiological_process
GO:0007399Nervous system developmentIEAbiological_process
GO:0017080Sodium channel regulator activityIDAmolecular_function
GO:0035725Sodium ion transmembrane transportIDAbiological_process
GO:0046684Response to pyrethroidIEAbiological_process
GO:0060048Cardiac muscle contractionIMPbiological_process
GO:0060371Regulation of atrial cardiac muscle cell membrane depolarizationIMPbiological_process
GO:0086002Cardiac muscle cell action potential involved in contractionIMPbiological_process
GO:0086006Voltage-gated sodium channel activity involved in cardiac muscle cell action potentialIMPmolecular_function
GO:0086012Membrane depolarization during cardiac muscle cell action potentialIMPbiological_process
GO:0086091Regulation of heart rate by cardiac conductionIMPbiological_process
GO:2000649Regulation of sodium ion transmembrane transporter activityIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.69929745450.52465009690.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.0164370054
GSE13712_SHEARDown-0.0722690302
GSE13712_STATICDown-0.1310283841
GSE19018Up0.1055496350
GSE19899_A1Down-0.0348081578
GSE19899_A2Up0.1008795467
PubMed_21979375_A1Down-0.0676987723
PubMed_21979375_A2Down-0.0224977070
GSE35957Up0.0258354050
GSE36640Down-0.0754264982
GSE54402Down-0.0975033874
GSE9593Up0.0365281823
GSE43922Up0.0203023649
GSE24585Up0.1003281541
GSE37065Down-0.0195757161
GSE28863_A1Up0.1489244598
GSE28863_A2Down-0.2308879873
GSE28863_A3Up0.1514953672
GSE28863_A4Up0.1463686989
GSE48662Down-0.0358355108

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Name

Drug

Accession number

ZonisamideDB00909 APRD00004

  • MicroRNAs

  • mirTarBase
No target information from mirTarBase
  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.