HCSGD entry for SBF1
1. General information
| Official gene symbol | SBF1 |
|---|---|
| Entrez ID | 6305 |
| Gene full name | SET binding factor 1 |
| Other gene symbols | DENND7A MTMR5 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0006470 | Protein dephosphorylation | TAS | biological_process |
| GO:0007283 | Spermatogenesis | IEA | biological_process |
| GO:0008138 | Protein tyrosine/serine/threonine phosphatase activity | TAS | molecular_function |
| GO:0008219 | Cell death | IEA | biological_process |
| GO:0016021 | Integral component of membrane | TAS | cellular_component |
| GO:0016791 | Phosphatase activity | IEA | molecular_function |
| GO:0017112 | Rab guanyl-nucleotide exchange factor activity | IDA | molecular_function |
| GO:0032313 | Regulation of Rab GTPase activity | IDA | biological_process |
| GO:0032318 | Regulation of Ras GTPase activity | IDA | biological_process |
| GO:0043087 | Regulation of GTPase activity | IDA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3968577410 | 0.7340260400 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0295966750 |
| GSE13712_SHEAR | Down | -0.0408913338 |
| GSE13712_STATIC | Down | -0.1078291853 |
| GSE19018 | Up | 0.0559648116 |
| GSE19899_A1 | Down | -0.0210527319 |
| GSE19899_A2 | Up | 0.0411024568 |
| PubMed_21979375_A1 | Up | 0.0215689415 |
| PubMed_21979375_A2 | Up | 0.8489756354 |
| GSE35957 | Down | -0.0716130407 |
| GSE36640 | Up | 0.2187040272 |
| GSE54402 | Up | 0.0669750024 |
| GSE9593 | Up | 0.0745098596 |
| GSE43922 | Up | 0.0658724256 |
| GSE24585 | Down | -0.0749128899 |
| GSE37065 | Down | -0.3736922849 |
| GSE28863_A1 | Down | -0.1339788685 |
| GSE28863_A2 | Down | -0.0328927881 |
| GSE28863_A3 | Up | 0.3360990982 |
| GSE28863_A4 | Up | 0.1068503566 |
| GSE48662 | Up | 0.1130994561 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-877-3p | MIMAT0004950 | MIRT037199 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-744-5p | MIMAT0004945 | MIRT037625 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038372 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-503-5p | MIMAT0002874 | MIRT041127 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-346 | MIMAT0000773 | MIRT042710 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-324-3p | MIMAT0000762 | MIRT042986 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044578 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045439 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046284 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-196a-5p | MIMAT0000226 | MIRT048226 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-16-5p | MIMAT0000069 | MIRT051209 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
