HCSGD entry for RRBP1


1. General information

Official gene symbolRRBP1
Entrez ID6238
Gene full nameribosome binding protein 1
Other gene symbolsES/130 ES130 RRp hES
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0004872Receptor activityTASmolecular_function
GO:0005783Endoplasmic reticulumIDAcellular_component
GO:0005840RibosomeTAScellular_component
GO:0006412TranslationTASbiological_process
GO:0015031Protein transportIEAbiological_process
GO:0030176Integral component of endoplasmic reticulum membraneIEAcellular_component
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.34632144300.62692683030.99999024731.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Down-0.0927405296
GSE13712_SHEARUp0.1241791273
GSE13712_STATICDown-0.0337929673
GSE19018Down-0.2912132912
GSE19899_A1Down-0.1077807021
GSE19899_A2Down-0.2200271151
PubMed_21979375_A1Up0.2396610026
PubMed_21979375_A2Down-0.0131457377
GSE35957Down-0.2472173236
GSE36640Up0.4297772882
GSE54402Down-0.2496729243
GSE9593Up0.0054027673
GSE43922Up0.0826461973
GSE24585Up0.0221235585
GSE37065Down-0.2991874653
GSE28863_A1Up0.3434031581
GSE28863_A2Up0.3809809251
GSE28863_A3Up0.1910100447
GSE28863_A4Up0.1364884325
GSE48662Up0.5950166895

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-1MIMAT0000416MIRT005285pSILAC//Proteomics;OtherFunctional MTI (Weak)18668040
hsa-miR-335-5pMIMAT0000765MIRT016910MicroarrayFunctional MTI (Weak)18185580
hsa-miR-34a-5pMIMAT0000255MIRT025298ProteomicsFunctional MTI (Weak)21566225
hsa-miR-331-3pMIMAT0000760MIRT043513CLASHFunctional MTI (Weak)23622248
hsa-miR-92a-3pMIMAT0000092MIRT049448CLASHFunctional MTI (Weak)23622248
hsa-let-7b-5pMIMAT0000063MIRT052004CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: 1 abstracts the gene occurs.


PubMed ID of the article

Sentenece the gene occurs

24763337We found that HP1beta mobility is similar in human embryonic stem cells (hES) and iPS cells where it is more mobile compared to fibroblasts; HP1beta is less mobile in senescent fibroblasts than in young (dividing) fibroblasts
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