HCSGD entry for RPS21

1. General information

Official gene symbolRPS21
Entrez ID6227
Gene full nameribosomal protein S21
Other gene symbolsS21
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0000184Nuclear-transcribed mRNA catabolic process, nonsense-mediated decayTASbiological_process
GO:0000447Endonucleolytic cleavage in ITS1 to separate SSU-rRNA from 5.8S rRNA and LSU-rRNA from tricistronic rRNA transcript (SSU-rRNA, 5.8S rRNA, LSU-rRNA)IBAbiological_process
GO:0000461Endonucleolytic cleavage to generate mature 3'-end of SSU-rRNA from (SSU-rRNA, 5.8S rRNA, LSU-rRNA)IBAbiological_process
GO:0003735Structural constituent of ribosomeIBA IEAmolecular_function
GO:0005737CytoplasmIDAcellular_component
GO:0005829CytosolTAScellular_component
GO:0005840RibosomeIEAcellular_component
GO:0006412TranslationIC IEA NAS TASbiological_process
GO:0006413Translational initiationTASbiological_process
GO:0006414Translational elongationTASbiological_process
GO:0006415Translational terminationTASbiological_process
GO:0006614SRP-dependent cotranslational protein targeting to membraneTASbiological_process
GO:0010467Gene expressionTASbiological_process
GO:0015935Small ribosomal subunitIDAcellular_component
GO:0016032Viral processTASbiological_process
GO:0016070RNA metabolic processTASbiological_process
GO:0016071MRNA metabolic processTASbiological_process
GO:0019058Viral life cycleTASbiological_process
GO:0019083Viral transcriptionTASbiological_process
GO:0022627Cytosolic small ribosomal subunitIDA NAScellular_component
GO:0042274Ribosomal small subunit biogenesisIBAbiological_process
GO:0044267Cellular protein metabolic processTASbiological_process
GO:0047485Protein N-terminus bindingIPImolecular_function
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.35214384710.13926087910.99999024730.7186572129

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1590417927
GSE13712_SHEARDown-0.1766229255
GSE13712_STATICDown-0.0017536043
GSE19018Down-0.2156288724
GSE19899_A1Up0.2366730141
GSE19899_A2Up0.3178820132
PubMed_21979375_A1Up0.5262556875
PubMed_21979375_A2Down-0.0236884074
GSE35957Up0.0181212239
GSE36640Down-0.6106149500
GSE54402Up0.3847490818
GSE9593Down-0.1323703502
GSE43922Up0.2014956173
GSE24585Down-0.2715768474
GSE37065Down-0.4034351387
GSE28863_A1Down-0.4887952273
GSE28863_A2Down-0.3533307341
GSE28863_A3Down-0.0047717822
GSE28863_A4Up0.3413768498
GSE48662Down-0.4563059199

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-186-5pMIMAT0000456MIRT044996CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.