HCSGD entry for RPS6KB2
1. General information
| Official gene symbol | RPS6KB2 |
|---|---|
| Entrez ID | 6199 |
| Gene full name | ribosomal protein S6 kinase, 70kDa, polypeptide 2 |
| Other gene symbols | KLS P70-beta P70-beta-1 P70-beta-2 S6K-beta2 S6K2 SRK STK14B p70(S6K)-beta p70S6Kb |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0004672 | Protein kinase activity | IEA TAS | molecular_function |
| GO:0004674 | Protein serine/threonine kinase activity | TAS | molecular_function |
| GO:0004711 | Ribosomal protein S6 kinase activity | IEA | molecular_function |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0005654 | Nucleoplasm | TAS | cellular_component |
| GO:0005737 | Cytoplasm | IEA | cellular_component |
| GO:0005840 | Ribosome | IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0007165 | Signal transduction | TAS | biological_process |
| GO:0007173 | Epidermal growth factor receptor signaling pathway | TAS | biological_process |
| GO:0008543 | Fibroblast growth factor receptor signaling pathway | TAS | biological_process |
| GO:0038095 | Fc-epsilon receptor signaling pathway | TAS | biological_process |
| GO:0042277 | Peptide binding | IEA | molecular_function |
| GO:0043491 | Protein kinase B signaling | IEA | biological_process |
| GO:0045087 | Innate immune response | TAS | biological_process |
| GO:0045948 | Positive regulation of translational initiation | IMP | biological_process |
| GO:0048011 | Neurotrophin TRK receptor signaling pathway | TAS | biological_process |
| GO:0048015 | Phosphatidylinositol-mediated signaling | TAS | biological_process |
Entries Per Page
Displaying Page of
4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.3882554804 | 0.3263329433 | 0.9999902473 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0904424860 |
| GSE13712_SHEAR | Up | 0.3082868546 |
| GSE13712_STATIC | Up | 0.1357268840 |
| GSE19018 | Up | 0.0182119464 |
| GSE19899_A1 | Down | -0.3093547516 |
| GSE19899_A2 | Up | 0.3471965877 |
| PubMed_21979375_A1 | Up | 0.0404800079 |
| PubMed_21979375_A2 | Up | 0.9138506857 |
| GSE35957 | Up | 0.0065240193 |
| GSE36640 | Up | 0.1799173294 |
| GSE54402 | Up | 0.2988043987 |
| GSE9593 | Up | 0.0474052553 |
| GSE43922 | Down | -0.0008008380 |
| GSE24585 | Down | -0.1758229869 |
| GSE37065 | Down | -0.1317600926 |
| GSE28863_A1 | Down | -0.2964112162 |
| GSE28863_A2 | Down | -0.3302829896 |
| GSE28863_A3 | Down | -0.4260222806 |
| GSE28863_A4 | Down | -0.0205533152 |
| GSE48662 | Down | -0.0061525735 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-98-5p | MIMAT0000096 | MIRT027691 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-26b-5p | MIMAT0000083 | MIRT029811 | Microarray | Functional MTI (Weak) | 19088304 |
| hsa-miR-1296-5p | MIMAT0005794 | MIRT036102 | CLASH | Functional MTI (Weak) | 23622248 |
Entries Per Page
Displaying Page of
- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
