HCSGD entry for RPN2
1. General information
| Official gene symbol | RPN2 |
|---|---|
| Entrez ID | 6185 |
| Gene full name | ribophorin II |
| Other gene symbols | RIBIIR RPN-II RPNII SWP1 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000421 | Autophagic vacuole membrane | IEA | cellular_component |
| GO:0004579 | Dolichyl-diphosphooligosaccharide-protein glycotransferase activity | NAS | molecular_function |
| GO:0005634 | Nucleus | IDA | cellular_component |
| GO:0005783 | Endoplasmic reticulum | IDA | cellular_component |
| GO:0005789 | Endoplasmic reticulum membrane | TAS | cellular_component |
| GO:0005791 | Rough endoplasmic reticulum | IEA | cellular_component |
| GO:0006412 | Translation | TAS | biological_process |
| GO:0006464 | Cellular protein modification process | TAS | biological_process |
| GO:0006487 | Protein N-linked glycosylation | IEA | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0007568 | Aging | IEA | biological_process |
| GO:0008250 | Oligosaccharyltransferase complex | IEA TAS | cellular_component |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016021 | Integral component of membrane | IEA | cellular_component |
| GO:0018279 | Protein N-linked glycosylation via asparagine | NAS TAS | biological_process |
| GO:0042493 | Response to drug | IEA | biological_process |
| GO:0043022 | Ribosome binding | IEA | molecular_function |
| GO:0043687 | Post-translational protein modification | TAS | biological_process |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.2515862277 | 0.6663943733 | 0.9414275092 | 1.0000000000 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Up | 0.0796662159 |
| GSE13712_SHEAR | Up | 0.0772917383 |
| GSE13712_STATIC | Down | -0.0428417146 |
| GSE19018 | Up | 1.0603665262 |
| GSE19899_A1 | Down | -0.2821157100 |
| GSE19899_A2 | Up | 0.0228705069 |
| PubMed_21979375_A1 | Down | -0.1343760286 |
| PubMed_21979375_A2 | Down | -0.1843588067 |
| GSE35957 | Down | -0.3970064976 |
| GSE36640 | Up | 0.4714841902 |
| GSE54402 | Down | -0.3440453443 |
| GSE9593 | Up | 0.2049863307 |
| GSE43922 | Down | -0.0432947971 |
| GSE24585 | Up | 0.2036867857 |
| GSE37065 | Up | 0.1642721758 |
| GSE28863_A1 | - | - |
| GSE28863_A2 | - | - |
| GSE28863_A3 | - | - |
| GSE28863_A4 | - | - |
| GSE48662 | Up | 0.4607283623 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-375 | MIMAT0000728 | MIRT019733 | Microarray | Functional MTI (Weak) | 20215506 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039690 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-484 | MIMAT0002174 | MIRT042274 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-23b-3p | MIMAT0000418 | MIRT046320 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30d-5p | MIMAT0000245 | MIRT047806 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-30a-5p | MIMAT0000087 | MIRT049944 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-let-7e-5p | MIMAT0000066 | MIRT051474 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
