HCSGD entry for MRPL12


1. General information

Official gene symbolMRPL12
Entrez ID6182
Gene full namemitochondrial ribosomal protein L12
Other gene symbols5c5-2 L12mt MRP-L31/34 MRPL7 MRPL7/L12 RPML12
Links to Entrez GeneLinks to Entrez Gene

2. Neighbors in the network

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This gene isn't in Literature mining network.

3. Gene ontology annotation

GO ID

GO term

Evidence

Category

GO:0003723RNA bindingTASmolecular_function
GO:0003735Structural constituent of ribosomeIEAmolecular_function
GO:0005515Protein bindingIPImolecular_function
GO:0005739MitochondrionIDAcellular_component
GO:0005762Mitochondrial large ribosomal subunitIDAcellular_component
GO:0006390Transcription from mitochondrial promoterIDAbiological_process
GO:0006412TranslationIEAbiological_process
GO:0045893Positive regulation of transcription, DNA-templatedIDAbiological_process
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4. Expression levels in datasets

  • Meta-analysis result

p-value upp-value downFDR upFDR down
0.28993931840.67159536490.98891963201.0000000000

  • Individual experiment result
    ( "-" represent NA in the specific microarray platform )

Data sourceUp or downLog fold change
GSE11954Up0.1968304842
GSE13712_SHEARUp0.3845001908
GSE13712_STATICUp0.3902806292
GSE19018Down-0.2174313871
GSE19899_A1Down-0.1125579679
GSE19899_A2Up0.1731354645
PubMed_21979375_A1Up1.8254855861
PubMed_21979375_A2Down-0.2816606341
GSE35957Down-0.4862814262
GSE36640Down-0.3132128495
GSE54402Up0.3799041729
GSE9593Down-0.3763557184
GSE43922--
GSE24585--
GSE37065--
GSE28863_A1--
GSE28863_A2--
GSE28863_A3--
GSE28863_A4--
GSE48662Up0.0171650749

5. Regulation relationships with compounds/drugs/microRNAs

  • Compounds

Not regulated by compounds

  • Drugs

Not regulated by drugs

  • MicroRNAs

  • mirTarBase

MiRNA_name

mirBase ID

miRTarBase ID

Experiment

Support type

References (Pubmed ID)

hsa-miR-98-5pMIMAT0000096MIRT027400MicroarrayFunctional MTI (Weak)19088304
hsa-miR-16-5pMIMAT0000069MIRT031389ProteomicsFunctional MTI (Weak)18668040
hsa-miR-423-3pMIMAT0001340MIRT042624CLASHFunctional MTI (Weak)23622248
hsa-miR-340-3pMIMAT0000750MIRT043855CLASHFunctional MTI (Weak)23622248
hsa-miR-107MIMAT0000104MIRT048289CLASHFunctional MTI (Weak)23622248
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  • mirRecord
No target information from mirRecord

6. Text-mining results about the gene

Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.