HCSGD entry for RPL15
1. General information
| Official gene symbol | RPL15 |
|---|---|
| Entrez ID | 6138 |
| Gene full name | ribosomal protein L15 |
| Other gene symbols | EC45 L15 RPL10 RPLY10 RPYL10 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0003735 | Structural constituent of ribosome | IEA NAS | molecular_function |
| GO:0005515 | Protein binding | IPI | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005840 | Ribosome | IEA TAS | cellular_component |
| GO:0006412 | Translation | IEA NAS TAS | biological_process |
| GO:0006413 | Translational initiation | TAS | biological_process |
| GO:0006414 | Translational elongation | TAS | biological_process |
| GO:0006415 | Translational termination | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0019058 | Viral life cycle | TAS | biological_process |
| GO:0019083 | Viral transcription | TAS | biological_process |
| GO:0022625 | Cytosolic large ribosomal subunit | IDA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9408885947 | 0.0801331180 | 0.9999902473 | 0.5354617416 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0045275097 |
| GSE13712_SHEAR | Down | -0.5827139937 |
| GSE13712_STATIC | Down | -0.5010377801 |
| GSE19018 | Up | 0.1821110623 |
| GSE19899_A1 | Down | -0.0891579478 |
| GSE19899_A2 | Down | -0.1242491493 |
| PubMed_21979375_A1 | Up | 0.0525827967 |
| PubMed_21979375_A2 | Down | -0.3720025559 |
| GSE35957 | Up | 0.0247626133 |
| GSE36640 | Down | -0.1897159120 |
| GSE54402 | Up | 0.0944456265 |
| GSE9593 | Down | -0.0066819907 |
| GSE43922 | Down | -0.1648866427 |
| GSE24585 | Up | 0.2821019259 |
| GSE37065 | Down | -0.2207119437 |
| GSE28863_A1 | Up | 0.2207990022 |
| GSE28863_A2 | Down | -0.2023939806 |
| GSE28863_A3 | Down | -0.4538359026 |
| GSE28863_A4 | Up | 0.1193608451 |
| GSE48662 | Down | -0.5164899283 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Alpha-Hydroxy-Beta-Phenyl-Propionic Acid | DB02494 | EXPT01733 |
| Anisomycin | DB07374 | - |
| Puromycin | DB08437 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-7-5p | MIMAT0000252 | MIRT025638 | Microarray | Functional MTI (Weak) | 19073608 |
| hsa-miR-7-5p | MIMAT0000252 | MIRT025638 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-221-5p | MIMAT0004568 | MIRT038663 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-20a-3p | MIMAT0004493 | MIRT038970 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-615-3p | MIMAT0003283 | MIRT039682 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-503-5p | MIMAT0002874 | MIRT041107 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-342-3p | MIMAT0000753 | MIRT043689 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-149-5p | MIMAT0000450 | MIRT045391 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-221-3p | MIMAT0000278 | MIRT046869 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-10a-5p | MIMAT0000253 | MIRT047531 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-100-5p | MIMAT0000098 | MIRT048511 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049215 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
