HCSGD entry for RPL8
1. General information
| Official gene symbol | RPL8 |
|---|---|
| Entrez ID | 6132 |
| Gene full name | ribosomal protein L8 |
| Other gene symbols | L8 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000184 | Nuclear-transcribed mRNA catabolic process, nonsense-mediated decay | TAS | biological_process |
| GO:0003723 | RNA binding | TAS | molecular_function |
| GO:0003735 | Structural constituent of ribosome | IEA NAS | molecular_function |
| GO:0005829 | Cytosol | TAS | cellular_component |
| GO:0005840 | Ribosome | IEA | cellular_component |
| GO:0006412 | Translation | IEA NAS TAS | biological_process |
| GO:0006413 | Translational initiation | TAS | biological_process |
| GO:0006414 | Translational elongation | TAS | biological_process |
| GO:0006415 | Translational termination | TAS | biological_process |
| GO:0006614 | SRP-dependent cotranslational protein targeting to membrane | TAS | biological_process |
| GO:0010467 | Gene expression | TAS | biological_process |
| GO:0016032 | Viral process | TAS | biological_process |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0016071 | MRNA metabolic process | TAS | biological_process |
| GO:0019058 | Viral life cycle | TAS | biological_process |
| GO:0019083 | Viral transcription | TAS | biological_process |
| GO:0019843 | RRNA binding | IEA | molecular_function |
| GO:0022625 | Cytosolic large ribosomal subunit | IDA | cellular_component |
| GO:0044267 | Cellular protein metabolic process | TAS | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9630490825 | 0.1610697390 | 0.9999902473 | 0.7745200767 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0155030485 |
| GSE13712_SHEAR | Down | -0.2340878102 |
| GSE13712_STATIC | Down | -0.1852535048 |
| GSE19018 | Up | 0.2174669705 |
| GSE19899_A1 | Down | -0.0179215378 |
| GSE19899_A2 | Down | -0.0607526237 |
| PubMed_21979375_A1 | Up | 0.1341705395 |
| PubMed_21979375_A2 | Down | -0.2555450139 |
| GSE35957 | Down | -0.4973447870 |
| GSE36640 | Down | -0.6391417116 |
| GSE54402 | Up | 0.1007330136 |
| GSE9593 | Down | -0.1398115575 |
| GSE43922 | Up | 0.0482009196 |
| GSE24585 | Up | 0.0717112686 |
| GSE37065 | Down | -0.2260073540 |
| GSE28863_A1 | Down | -0.2358756053 |
| GSE28863_A2 | Down | -0.1650891483 |
| GSE28863_A3 | Up | 0.1556892826 |
| GSE28863_A4 | Up | 0.0243291312 |
| GSE48662 | Down | -0.3099063105 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Name | Drug | Accession number |
|---|---|---|
| Alpha-Hydroxy-Beta-Phenyl-Propionic Acid | DB02494 | EXPT01733 |
| Anisomycin | DB07374 | - |
| Puromycin | DB08437 | - |
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-455-3p | MIMAT0004784 | MIRT037866 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-130b-5p | MIMAT0004680 | MIRT038297 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-296-3p | MIMAT0004679 | MIRT038359 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92b-3p | MIMAT0003218 | MIRT040617 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041298 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-320a | MIMAT0000510 | MIRT044588 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-222-3p | MIMAT0000279 | MIRT046643 | CLASH | Functional MTI (Weak) | 23622248 |
| hsa-miR-92a-3p | MIMAT0000092 | MIRT049424 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
