HCSGD entry for FKBP10
1. General information
| Official gene symbol | FKBP10 |
|---|---|
| Entrez ID | 60681 |
| Gene full name | FK506 binding protein 10, 65 kDa |
| Other gene symbols | FKBP65 OI11 OI6 PPIASE hFKBP65 |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000413 | Protein peptidyl-prolyl isomerization | IBA | biological_process |
| GO:0003755 | Peptidyl-prolyl cis-trans isomerase activity | IBA IEA | molecular_function |
| GO:0005509 | Calcium ion binding | IEA | molecular_function |
| GO:0005528 | FK506 binding | IBA | molecular_function |
| GO:0005788 | Endoplasmic reticulum lumen | IEA | cellular_component |
| GO:0006457 | Protein folding | IEA | biological_process |
| GO:0016020 | Membrane | IBA | cellular_component |
| GO:0018208 | Peptidyl-proline modification | IBA | biological_process |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.5788668326 | 0.0277148627 | 0.9999902473 | 0.3169559896 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.2103056797 |
| GSE13712_SHEAR | Down | -0.3235383913 |
| GSE13712_STATIC | Up | 0.1196155276 |
| GSE19018 | Up | 0.7424430696 |
| GSE19899_A1 | Down | -1.1224931265 |
| GSE19899_A2 | Down | -0.7280993451 |
| PubMed_21979375_A1 | Up | 0.2698435425 |
| PubMed_21979375_A2 | Down | -1.7976271171 |
| GSE35957 | Down | -0.0738957160 |
| GSE36640 | Up | 0.5118214835 |
| GSE54402 | Down | -0.4079915450 |
| GSE9593 | Up | 0.2369844511 |
| GSE43922 | Down | -0.3221747208 |
| GSE24585 | Down | -0.3895617102 |
| GSE37065 | Down | -0.1345868305 |
| GSE28863_A1 | Up | 0.0533315173 |
| GSE28863_A2 | Down | -0.0059661285 |
| GSE28863_A3 | Down | -0.4493500209 |
| GSE28863_A4 | Up | 0.0713858831 |
| GSE48662 | Up | 0.4136926832 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-132-3p | MIMAT0000426 | MIRT021739 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-128-3p | MIMAT0000424 | MIRT021875 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-miR-181a-5p | MIMAT0000256 | MIRT025084 | Microarray | Functional MTI (Weak) | 17612493 |
| hsa-let-7c-5p | MIMAT0000064 | MIRT051795 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
