HCSGD entry for EEFSEC
1. General information
| Official gene symbol | EEFSEC |
|---|---|
| Entrez ID | 60678 |
| Gene full name | eukaryotic elongation factor, selenocysteine-tRNA-specific |
| Other gene symbols | EFSEC SELB |
| Links to Entrez Gene | Links to Entrez Gene |
2. Neighbors in the network
This gene isn't in Literature mining network.
3. Gene ontology annotation
GO ID | GO term | Evidence | Category |
|---|---|---|---|
| GO:0000049 | TRNA binding | IEA | molecular_function |
| GO:0001514 | Selenocysteine incorporation | IEA | biological_process |
| GO:0003746 | Translation elongation factor activity | IEA | molecular_function |
| GO:0003924 | GTPase activity | IEA | molecular_function |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005634 | Nucleus | IEA | cellular_component |
| GO:0005739 | Mitochondrion | IEA | cellular_component |
| GO:0030529 | Ribonucleoprotein complex | IEA | cellular_component |
| GO:0035368 | Selenocysteine insertion sequence binding | IEA | molecular_function |
| GO:0043021 | Ribonucleoprotein complex binding | IEA | molecular_function |
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4. Expression levels in datasets
- Meta-analysis result
| p-value up | p-value down | FDR up | FDR down |
|---|---|---|---|
| 0.9394878310 | 0.1218800198 | 0.9999902473 | 0.6700586358 |
- Individual experiment result
( "-" represent NA in the specific microarray platform )
( "-" represent NA in the specific microarray platform )
| Data source | Up or down | Log fold change |
|---|---|---|
| GSE11954 | Down | -0.0975032226 |
| GSE13712_SHEAR | Up | 0.0390158359 |
| GSE13712_STATIC | Up | 0.1369648945 |
| GSE19018 | Up | 0.3082157692 |
| GSE19899_A1 | Down | -0.4126690931 |
| GSE19899_A2 | Down | -0.0545788016 |
| PubMed_21979375_A1 | Down | -0.4273433471 |
| PubMed_21979375_A2 | Down | -0.3504681233 |
| GSE35957 | Down | -0.5742330881 |
| GSE36640 | Down | -0.1762721932 |
| GSE54402 | Down | -0.1005667515 |
| GSE9593 | Down | -0.6714678059 |
| GSE43922 | Down | -0.3209873512 |
| GSE24585 | Up | 0.0823631129 |
| GSE37065 | Up | 0.0302815157 |
| GSE28863_A1 | Up | 0.0309519891 |
| GSE28863_A2 | Up | 0.1199894436 |
| GSE28863_A3 | Up | 0.0088255096 |
| GSE28863_A4 | Down | -0.0906133918 |
| GSE48662 | Up | 0.1287426840 |
5. Regulation relationships with compounds/drugs/microRNAs
- Compounds
Not regulated by compounds
- Drugs
Not regulated by drugs
- MicroRNAs
- mirTarBase
MiRNA_name | mirBase ID | miRTarBase ID | Experiment | Support type | References (Pubmed ID) |
|---|---|---|---|---|---|
| hsa-miR-193b-3p | MIMAT0002819 | MIRT041486 | CLASH | Functional MTI (Weak) | 23622248 |
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- mirRecord
No target information from mirRecord
6. Text-mining results about the gene
Gene occurances in abstracts of cellular senescence-associated articles: This gene isn't in text-mining gene-sentence result.
